Development and Optimization of Finasteride-Loaded Microemulsions for Transdermal Delivery

    December 2019
    Napapat Rattanachitthawat, นปภัช รัตนะชิตธวัช, Tanasait Ngawhirunpat, ธนะเศรษฐ์ ง้าวหิรัญพัฒน์
    Studysummary This study found that finasteride could enhance the stemness of dermal papilla cells, suggesting potential benefits for hair regeneration approaches.
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    Research cited in this study 14

    1. Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment Fitoterapia · 2016
    2. Glycyrrhizic Acid Attenuates Stem Cell-Like Phenotypes of Human Dermal Papilla Cells Phytomedicine · 2015
    3. Chitosan-Decorated Polystyrene-b-Poly(Acrylic Acid) Polymersomes as Novel Carriers for Topical Delivery of Finasteride European Journal of Pharmaceutical Sciences · 2013
    4. Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery Aaps Pharmscitech · 2012
    5. Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia British Journal of Dermatology · 2012
    6. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    7. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    8. Scalp Dermoscopy of Androgenetic Alopecia in Asian People Journal of Dermatology · 2009
    9. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    10. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    11. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    12. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    13. Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles Journal of Investigative Dermatology · 2000
    14. Topical Minoxidil in Male Pattern Baldness: Effects of Discontinuation of Treatment Journal of The American Academy of Dermatology · 1987

    Related research 2

    1. Dermal and Transdermal Drug Delivery Through Vesicles and Particles: Preparation and Applications Advanced Pharmaceutical Bulletin · 2021
    2. Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers Pharmaceutical nanotechnology · 2013