47 citations
,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
21 citations
,
November 2015 in “Phytomedicine” Glycyrrhizic acid may help reduce unwanted hair growth.
52 citations
,
November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
58 citations
,
December 2012 in “Aaps Pharmscitech” LCN may improve finasteride delivery for hair loss treatment.
95 citations
,
January 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
68 citations
,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
338 citations
,
July 2009 in “Development” The study demonstrated that Sox2-positive dermal papilla cells played a crucial role in specifying hair follicle types in mammalian epidermis. Sox2 was initially expressed in all dermal papillae at E16.5, but later became restricted to certain types, specifically in guard/awl/auchene follicles in postnatal skin. The research utilized transgenic mice to isolate and compare Sox2+ (GFP+) CD133+ cells with Sox2- (GFP-) CD133+ cells, revealing distinct gene expression profiles and pathway activations. Sox2+ cells were associated with Wnt, FGF, and BMP pathways, while Sox2- cells were linked to hedgehog, IGF, Notch, and integrin pathways. Skin reconstitution assays showed that the absence of Sox2+ CD133+ cells led to the failure of awl/auchene hair formation, highlighting the importance of Sox2-positive cells in determining specific hair follicle types.
67 citations
,
February 2009 in “Journal of Dermatology” 
142 citations
,
August 2007 in “Journal of The American Academy of Dermatology” New 5% minoxidil foam effectively promotes hair growth and is safe for use.
829 citations
,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
127 citations
,
June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
229 citations
,
August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
57 citations
,
July 1987 in “Journal of The American Academy of Dermatology” Stopping minoxidil treatment resumes balding; continuous use needed for results.
