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    Did you mean Stem Cell Factor?
    Glossary Stem Cell Factor

    protein crucial for stem cell survival and differentiation

    Stem Cell Factor (SCF), also known as Kit Ligand, is a protein that plays a crucial role in the survival, proliferation, and differentiation of hematopoietic stem cells, which are the cells responsible for forming blood. SCF binds to the c-Kit receptor on the surface of these stem cells, activating signaling pathways that are essential for their function and maintenance. This factor is also important in other biological processes, including pigmentation, fertility, and the development of certain cell types in the immune system.

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    Research 10 of 1000+

    1. The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells International Journal of Molecular Sciences · 2020 · 3 citations
    2. Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts Laboratory Investigation · 2006 · 27 citations
    3. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    4. SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling Journal of Investigative Dermatology · 2024 · 4 citations
    5. Efficacy of Platelet-Rich Plasma versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study Skin Appendage Disorders · 2024
    6. Immunohistochemical study assessing stem cell factor receptor C-kit in patients with alopecia Egyptian Journal of Dermatology and Venereology · 2020
    7. Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles Journal of Endocrinology · 2008 · 39 citations
    8. Potential Involvement of the Stem Cell Factor Receptor c-kit in Alopecia Areata and Androgenetic Alopecia: Histopathological, Immunohistochemical, and Semiquantitative Investigations Acta Histochemica Et Cytochemica · 2010 · 10 citations
    9. Stem cell factor combined with matrix proteins promotes attachment and migration of amelanotic melanocyte from human follicle hair Linchuang pifuke zazhi · 2006
    10. Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice Nature · 2015 · 321 citations
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    Community 10 of 185

    1. Scalp Microneedling with Stemcell and Exohealer Reddit · 12 Jun 2026
    2. Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth Reddit · 22 Sept 2024
    3. NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress Reddit · 9 Jun 2024
    4. 12 mo 1 ml daily Min/Dermaroller 1mm-1.5mm update + AGA progression theory and specific order of treatment Reddit · 22 Jan 2021
    5. How Does Exosome Therapy Work for Hair Loss? Reddit · 13 Oct 2023
    6. Physio-metabolic method (antiandrogen, minoxidil, leg training and cold) Community · 7 Jun 2024
    7. Starting the microneedling only journey. M35 with diffuse thinning. Derminator 2, keto, vitamins and castor oil. Reddit · 31 Mar 2022
    8. Anyone Try Microneedling with Exosomes/AAPE? Reddit · 6 May 2022
    9. Stem cells for hair, does it work? Reddit · 30 Nov 2025
    10. Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways. Reddit · 24 Aug 2026
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