52 citations
,
June 2009 in “Clinical Toxicology” This article reviews the clinical features, diagnosis, and treatment of acute radiation syndrome caused by ingesting (210)polonium, emphasizing the need for supportive care and potential benefits of chelation therapy.
8 citations
,
January 2018 in “Journal of Analytical Methods in Chemistry” This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” This article discusses the potential for combining PROTACs with other therapeutic modalities in drug discovery and reports no clinical results.
January 2026 in “Food Science and Human Wellness” This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.
January 2016 in “International journal of advanced research in chemical sciences” This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.
April 2007 in “Oncology Times” This research observed that both patients and primary care physicians are hesitant to fully embrace chemoprevention for cancer due to concerns over risk identification, side effects, and a lack of definitive guidance.
8 citations
,
January 1977 in “Acta Haematologica” This study found that the PVP protocol, combining Peptichemio, vincristine, and 6-methylprednisolone, resulted in remission for diffuse non-Hodgkin's lymphomas with moderate side effects.
February 2025 in “Frontiers in Veterinary Science” This case report highlights the successful use of Prussian Blue to treat a dog suffering from thallium intoxication, demonstrating the importance of early diagnosis and targeted therapy in veterinary care for improving recovery outcomes.
3 citations
,
January 2003 in “Synthetic Communications” This research describes the synthesis of 16β-chloro- and 16β-bromo-cyproterone acetate, detailing the chemical processes involved, but reports no clinical outcomes.
January 2023 in “Indian Journal of Forensic and Community Medicine” This report describes two cases of thallium poisoning with gastrointestinal symptoms, peripheral neuropathy, and alopecia, which were effectively treated using activated charcoal, potassium chloride, and hemodialysis.
81 citations
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February 2000 in “Anti-cancer drugs” In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
1 citations
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January 2004 in “Drugs” Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
28 citations
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October 1987 in “PubMed” This study found that treating Tradescantia stamen hair cells with LiCl disrupts mitotic progression, leading to metaphase arrest, which can be reversed by myo-inositol or CaCl2 addition.
July 1994 in “Annals of Pharmacotherapy” Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
9 citations
,
June 2017 in “Pharmacological Reports” This study found that ATP-sensitive potassium channels may play a role in chloroquine-induced itching in mice, as channel openers reduced scratching behavior while a blocker reversed these effects.
January 2007 in “Journal of Instrumental Analysis” This study found that using headspace capillary gas chromatography effectively determined the levels of residual organic solvents, including chloroform and dichloromethane, in finasteride with good separation and detection limits.
2 citations
,
May 1985 in “Environmental Health Perspectives” This report examines the mechanisms by which TCDD affects human epidermal and carcinoma cells, aiming to create a risk assessment model for halogenated aromatic compounds, but presents no new clinical results.
16 citations
,
September 2018 in “Journal of Molecular Liquids” This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.
5 citations
,
June 2015 in “British Journal of Dermatology” This article discusses the role of lysophosphatidic acid-induced histamine release in generalized pruritus among patients with primary sclerosing cholangitis and reports no new clinical results.
3 citations
,
January 2025 in “Scientific Reports” This study found that treating asymptomatic or mild COVID-19 with cepharanthine did not significantly reduce the time to a negative test result, though 60 mg/day showed a non-significant trend needing further validation.
January 2002 in “Chinese Journal of Hospital Pharmacy” This study reports that finasteride chewable tablets may be effective in treating benign prostatic hyperplasia due to their stable formulation and ease of production.
14 citations
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February 1994 in “Tetrahedron Letters” This study found that using anhydrous cerium(III) chloride with alkyl Grignard reagents significantly improved the addition to sterically hindered 17-ketosteroids, resulting in high yields and stereoselectivity.
January 2010 in “Guoji yaoxue yanjiu zazhi” This review discusses thallium poisoning, its mechanisms, clinical symptoms, and treatment approaches, highlighting hemoperfusion as an effective method to eliminate absorbed thallium, though no new clinical results are presented.
January 2013 in “Chinese Journal of Hospital Pharmacy” This study developed a precise and sensitive HPLC-MS/MS method for analyzing the pharmacokinetics of perospirone hydrochloride in human plasma, establishing it as suitable for clinical studies.
1 citations
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February 2014 in “Analytical Letters” This study developed a fast and sensitive ultra-high performance liquid chromatography method to quantify ketoconazole in antidandruff emulsions, showing comparable results to labeled concentrations.
February 2017 in “Cancer Research” In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.
13 citations
,
April 2019 in “International journal of molecular sciences” This article reviews the potential of Acyzol, a zinc-containing drug, to treat and prevent zinc deficiency conditions, but it reports no new clinical findings.
25 citations
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October 2019 in “Journal of Endocrinological Investigation” This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.
60 citations
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August 1969 in “British Journal of Dermatology” This study used an autoradiographic technique to observe that germicides in surfactants are primarily deposited on the stratum corneum of guinea-pig and human skin.
15 citations
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May 2009 in “Steroids” This study found that progesterone derivatives with chlorine or bromine substituents were effective in inhibiting 5α-reductase activity in human prostate and exhibited antiandrogenic effects in hamster flank organs.