Case Report: Successful Treatment of a Thallium Sulfate Intoxication in a Dog with Use of Prussian Blue

    February 2025 in “ Frontiers in Veterinary Science
    Fergal M. McDermott, Anne A. Kan, Claudine C. Hunault, Joris H. Robben, Dylan W. de Lange, Marieke A. Dijkman
    TLDR Prussian Blue successfully treated thallium poisoning in a dog.
    This case report details the successful treatment of a 5-year-old miniature Schnauzer suffering from thallium sulfate intoxication using Prussian Blue, a chelating agent rarely used in veterinary medicine. The dog exhibited symptoms such as lethargy, anorexia, and progressive alopecia. Treatment included supportive care and a 15-day course of Prussian Blue, followed by 4 days of activated charcoal. Serum thallium levels decreased significantly, with a calculated elimination half-life of 2.8 days during treatment. The dog showed gradual improvement and fully recovered after 11 weeks. This case highlights the critical role of early diagnosis and targeted therapy with Prussian Blue in managing thallium intoxication in animals.
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