October 2021 in “Meditsinskiy sovet = Medical Council” This study found that cyproterone acetate treatment improved quality of life and reduced anxiety and depressive symptoms in women with skin manifestations of hyperandrogenism.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that apocynin restored COL17A1 expression in human keratinocytes and reduced UVB-induced cellular senescence, DNA damage, and cell cycle arrest.
1 citations
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November 2005 in “PubMed” This study found that continuous itraconazole therapy was more effective than pulse therapy for treating tinea capitis caused by Microsporum ferrugineum, with a higher cumulative cure rate and no significant adverse effects.
September 2024 in “Journal of the American Academy of Dermatology” This study found that a new compounded topical solution for alopecia was clinically tolerable and did not cause irritation, while also showing potential to enhance hair growth through fibroblast proliferation and gene expression.
28 citations
,
December 2001 in “European Journal of Pharmacology” This study found that the compound M50054 inhibits apoptosis by blocking caspase-3 activation and may improve chemotherapy-induced alopecia and hepatitis symptoms.
2 citations
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April 2023 in “Curēus” This study presents a case of a 24-year-old man who developed mild transaminitis and rhabdomyolysis within 24 hours of starting valproic acid for seizures, with symptom resolution following drug cessation.
November 2023 in “Journal of Cosmetic Dermatology” This study found that a 12-week topical treatment with a caffeine and Procapil 3% formulation effectively reduced hair loss by 26.9% and improved hair growth in men with androgenetic alopecia, without any reported adverse effects.
2 citations
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May 2016 in “Journal of Clinical Oncology” This study found that topical BPM31543 was safe, tolerable, and showed potential to reduce chemotherapy-induced alopecia at higher dosing levels among adult women with cancer receiving taxane-based chemotherapy.
70 citations
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January 2000 in “Drug Development Research” The researchers reported that a novel family of butyric acid prodrugs, including AN-9 and AN-10, showed potential for anticancer activity, hemoglobin expression induction, and hair follicle protection, with AN-9 in phase II trials.
This study found that local therapy with trichoriboside and trichosaccharide significantly increased cAMP levels in hair follicles of men with androgenic alopecia, with trichoriboside showing greater activity.
21 citations
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September 2010 in “Archives of Dermatology” This document provides a legal disclaimer and offers no research findings.
24 citations
,
July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
13 citations
,
October 2013 in “The Journal of Dermatology” This study found that topical cepharanthine increased IGF-I production in human dermal papilla cells, suggesting it may stimulate hair growth and be a promising treatment option for androgenetic alopecia.
October 2014 in “Cancer Research” This study observed that applying a GMP-grade botanical extract to the scalp increased Bcl-2 levels, potentially preventing premature hair follicle apoptosis in chemotherapy and radiotherapy-induced alopecia.
February 2026 in “European Journal of Pharmacology” In this study, teicoplanin significantly improved hair regrowth and follicle size in mice with dihydrotestosterone-induced androgenetic alopecia, suggesting its potential as a treatment option for hair loss due to its ability to enhance cell proliferation and decrease androgen receptor protein levels.
9 citations
,
October 2025 in “MedComm” This review discusses the development and clinical progression of PROTAC technology for targeted protein degradation, highlighting its potential to address previously "undruggable" targets but reports no new clinical results.
2 citations
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November 2004 in “Hospital pharmacy” This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.
July 2023 in “Journal of exploratory research in pharmacology” In this case report, a 47-year-old man with extensive psoriasis saw significant improvement in scaling and itching after using a new lotion containing clobetasol and other ingredients for one week, but further research is needed to confirm these findings.
11 citations
,
January 1997 in “Skin Pharmacology and Physiology” This study found that bisindolylmaleimide PKC inhibitors increased DNA synthesis in mouse hair follicles, suggesting that PKC may inhibit hair follicle proliferation.
22 citations
,
June 2018 in “Journal of Neuroinflammation” This study found that procyanidins effectively alleviate neuropathic pain in mice by significantly inhibiting MMP-9/2 activity.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.
13 citations
,
September 2021 in “Current Issues in Molecular Biology” This study suggests that D-panthenol may promote hair growth by enhancing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.
April 2023 in “Neurology” This study examined treatments for emesis in young Alexander disease patients, finding that 95% responded positively to valproic acid, which was more effective than anti-reflux medications or cyproheptadine, though some adverse effects require monitoring.
January 2023 in “World Journal of Clinical & Medical Images” This report discusses a late-onset case of Cronkhite-Canada syndrome that improved with prednisone treatment, highlighting the importance of early diagnosis to reduce life-threatening complications.
13 citations
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March 2020 in “Frontiers in cell and developmental biology” This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.
1 citations
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October 2024 in “The American Journal of Gastroenterology” In this case report, a patient with Crohn's disease experienced alopecia and psoriasiform reactions attributed to anti-TNF therapy, which improved after switching to Ustekinumab.
3 citations
,
April 2015 in “Current problems in dermatology” This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.
18 citations
,
January 2010 in “Dermatology Research and Practice” This case report describes a 30-year-old Brazilian male who developed vitiligo lesions following diphencyprone therapy for alopecia areata.
1 citations
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April 2012 in “Informa Healthcare eBooks” Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.
9 citations
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January 2017 in “Organic Process Research & Development” This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.