Protein-Losing Enteropathy, Anasarca and Dermatological Manifestations in Elderly: Consider Cronkhite-Canada Syndrome

Cronkhite-Canada syndrome is a rare, non-genetic condition with unknown causes, marked by gastrointestinal polyposis and a dermatological triad of nail dystrophy, hyperpigmentation, and alopecia, along with symptoms like diarrhea, weight loss, and abdominal pain. The document discusses a late-onset case that showed improvement with prednisone treatment. Early diagnosis is crucial to reduce the high morbidity and mortality rates associated with this potentially life-threatening syndrome.