2 citations
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February 2019 in “Journal of Investigative Dermatology” This study suggests that the expression of the DP2 receptor is higher in balding scalp cells and that its knockdown could inhibit the transition to the catagen phase in cultured human hair follicles, potentially counteracting hair growth inhibition associated with male pattern baldness.
January 2022 in “Pastic and aesthetic research” This article reviews the clinical use of platelet rich plasma for skin regeneration, highlighting the challenges of inconsistent outcomes due to varying preparation protocols, and calls for standardized models to better assess its effectiveness.
19 citations
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August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
14 citations
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March 2022 in “Plant Cell & Environment” In this study, the authors reported that AtRXR3, a phosphorus-inducible DUF506 protein, modulates root hair growth under phosphorus stress by interacting with calmodulin and influencing calcium oscillations.
76 citations
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June 2008 in “Journal of the American Academy of Dermatology” In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.
This overview of PRP Bristol clinics explains the growing popularity of Platelet-Rich Plasma therapy as a non-surgical treatment for early-stage hair loss, detailing its process, benefits, and suitability for individuals with androgenetic alopecia.
December 2019 in “Reproduction Fertility and Development” This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.
3 citations
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August 2020 in “PubMed” This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.
50 citations
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February 2004 in “Genomics” This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
July 2018 in “Hair transplant forum international” This study observed significant variation in platelet concentrations across four different platelet-rich plasma (PRP) systems, suggesting that PRP system choice may affect treatment outcomes for hair growth.
3 citations
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October 2021 in “Brain Sciences” This review hypothesizes that risperidone long-acting injectable may be linked to bullous pemphigoid in a bipolar patient, though current studies report mixed results.
1 citations
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July 2023 in “Aesthetic Plastic Surgery” This study discusses the potential psychological impact of platelet-rich plasma treatment for hair loss but reports no standardized protocols or conclusive results, highlighting the need for further analysis.
13 citations
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February 2024 in “Clinical Cosmetic and Investigational Dermatology” This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.
1 citations
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September 2016 in “Dermatologic Surgery” New hair loss subtype found, mimics common baldness.
April 2023 in “Journal of Investigative Dermatology” This review discusses randomized trials on PRP and laser therapy for vitiligo, acne scars, and skin rejuvenation, finding combination therapy may yield clinical improvements but calls for more diverse studies.
This research observed that removing RNase L in mice enhances regenerative capacity through increased IL-36 and wound-induced hair neogenesis, highlighting RNase L as a gene that represses regeneration by moderating immune responses during viral infections.
49 citations
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November 2021 in “Annual review of pathology” This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.
2 citations
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September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
December 2021 in “International Journal of Research in Dermatology” This review examines the use of platelet-rich plasma for treating alopecia and highlights current challenges in preparation standards and efficacy, without presenting new clinical findings.
September 2025 in “Clinical Case Reports” In this study, researchers suggested that adipose-derived exosomes could be a promising treatment option for lichen planopilaris, particularly in cases resistant to standard therapies, by potentially aiding in symptom management and hair preservation.
February 2026 in “JEADV Clinical Practice” This report describes a rare case of scarring alopecia, diagnosed as lichen planopilaris (LPP), affecting solely the limbs, highlighting the necessity for thorough evaluation of LPP beyond the scalp.
June 2017 in “Journal of The American Academy of Dermatology” Women in Australia report different signs of facial aging compared to women in the US, UK, and Canada; men with Lichen planopilaris often have hormonal abnormalities and thyroid disease.
May 2015 in “Hair transplant forum international” This article contains no research findings; it reports on an online discussion about platelet-rich plasma (PRP) and opinions shared during a conference.
1 citations
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March 2025 in “Journal of Cosmetic Dermatology” This case report describes promising results in treating poliosis circumscripta with exosomes and fractional picosecond laser, showing significant hair regrowth and repigmentation, though spontaneous repigmentation cannot be ruled out.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the loss of Langerhans cells in lichen planopilaris scars may be linked to the downregulation of ITG αvβ6, which is not seen in other scar formation diseases.
October 2024 in “Skin Appendage Disorders” This study found that lichen planopilaris is associated with several environmental factors, such as stress and hair dye use, as well as thyroid disorders and genetic components.
16 citations
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September 2006 in “Journal of Cutaneous Pathology” This study found that the p63 transcription factor is expressed during rat epidermal development and may serve as a specific marker for keratinocyte progenitor cells.
January 2026 in “Frontiers in Medicine” In this study, PP-PTKL exhibited antioxidant, anti-inflammatory, and pro-melanogenic effects in laboratory settings, suggesting its potential role in preventing or treating hair greying. Further animal and human studies are needed to verify these findings.
May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.
22 citations
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October 2018 in “Molecular Medicine Reports” In this study, classic PDRN (50-1,500 kDa) was observed to improve wound healing quality in a mouse model by enhancing collagen composition and cell migration.