31 citations
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October 2016 in “PLoS ONE” This study suggests that UMPP activation is a key signaling pathway in differentiating primary and secondary hair follicles in cashmere goats.
2 citations
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March 2019 in “Journal of Dermatology” This report describes a rare case of alopecia areata coexisting with primary scarring alopecia, diagnosed through detailed trichoscopic investigation, highlighting the importance of comprehensive examination for accurate diagnosis.
June 2020 in “Journal of Investigative Dermatology” This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.
16 citations
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December 2005 in “Journal of Animal Physiology and Animal Nutrition” This study found that both low and high dietary selenium levels reduced hair growth in adult dogs, with optimal growth observed at mid-range selenium concentrations.
2 citations
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August 2022 in “BMC veterinary research” This study confirmed the biological characteristics and multipotent differentiation potential of primary and secondary hair follicle stem cells from Arbas Cashmere goats, contributing to the understanding of adult stem cell types and characteristics.
1 citations
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July 2006 in “Journal of Investigative Dermatology” A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.
January 2016 in “Journal of animal research” This study found significant correlations for copper and zinc levels between hair and plasma in Pomeranian and Labrador dogs, but no significant correlation for iron.
January 2009 in “Anhui nongye kexue” This study found that higher concentrations of estradiol inhibited the growth of cashmere goat hair follicles, with associated morphological changes observed.
November 2023 in “BMJ case reports” Results are not reported in this abstract, which describes a man in his 30s with a 4-year history of patchy hair loss on the right lower leg and associated itching, highlighting the use of dermoscopy in his examination.
39 citations
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November 2009 in “Clinical and Experimental Dermatology” This study reports that in primary cicatricial alopecias, increased expression of certain immune markers in the hair-follicle bulge suggests a collapse of immune privilege, which may contribute to follicle destruction.
16 citations
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March 2021 in “Frontiers in cell and developmental biology” This study established an efficient short-term culture system for human hair follicle stem cells using human fibronectin and ROCK inhibitor Y-27632, enhancing cell proliferation and stemness for potential applications in hair follicle tissue engineering.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.
September 2024 in “Journal of Family Medicine and Primary Care” This study found that primary health physicians in Saudi Arabia generally have low knowledge and practice scores regarding the use of vitamins and minerals for treating hair loss, with no significant difference between more or less experienced doctors.
March 2015 in “Zagazig University Medical Journal” The study found that CK15 expression, representing hair follicle stem cell activity, was reduced or absent in scarred primary cicatricial alopecia lesions, suggesting stem cell damage may contribute to the scarring process.
1 citations
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January 2026 in “Physical review. D/Physical review. D.” In this study, researchers found that black holes with primary Proca hair exhibit distinctive optical properties, including a two-boundary shadow structure and additional inner rings, offering novel observational signatures and potential insights into strong-gravity environments.
27 citations
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September 2018 in “Skin appendage disorders” This review suggests that hair transplantation may be a viable treatment option for certain primary scarring alopecias, although findings should be interpreted cautiously due to possible publication bias favoring positive results.
14 citations
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August 2018 in “Frontiers in Cellular and Infection Microbiology” This study found that dengue virus infection caused inflammation and cell death in human hair-follicle dermal papilla cells, which may contribute to increased hair shedding observed during the epidemic in Taiwan.
12 citations
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January 2016 in “Skin appendage disorders” This review summarizes existing knowledge about hair restoration surgery for scarring alopecia but reports no new clinical results.
4 citations
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June 2007 in “PubMed” This study found that using engineered skin with PGA-collagen scaffolds, combined with hair follicle stem cells and other cell types, effectively repaired full-thickness skin defects in nude mice.
2 citations
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June 2020 in “Dermatologic Surgery” Fat grafting before hair transplant may improve hair growth in scarring alopecia.
September 2025 in “Surgeries” This review found that hair transplantation in patients with primary cicatricial alopecias is a viable option when the disease is stable, with outcomes varying significantly by subtype.
January 2019 in “Clinical pediatric dermatology” This review discusses the use of follicular unit extraction and scalp micropigmentation in treating male pattern baldness, noting that scalp micropigmentation provides a non-surgical option to emulate natural hair appearance without downtime.
2 citations
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October 2015 in “Primary Care: Clinics in Office Practice” This article discusses the evaluation and treatment options for alopecia but reports no new clinical results; it highlights the importance of early diagnosis and appropriate treatment.
42 citations
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July 2010 in “European Journal of Cell Biology” This study found that thyroid hormones T3 and T4 enhance keratin 15 promoter activity and stimulate CD200 expression in epithelial stem cells from human scalp hair follicles, affecting their growth and differentiation.
May 2023 in “Cytotherapy” This study found that medium/large extracellular vesicles derived from hair follicle and adipose tissue mesenchymal stromal cells both demonstrated significant neuroprotective and anti-inflammatory effects in cell cultures, highlighting their potential use as biopharmaceuticals for treating neurodegenerative diseases.
8 citations
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July 2021 in “Journal of Pediatric Health Care” In this paper, the authors provide recommendations for primary care practitioners on evaluating and treating pediatric hair loss, emphasizing the importance of early diagnosis to prevent permanent scarring alopecia by classifying causes into acquired or congenital origins.
6 citations
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May 1987 in “Acta dermato-venereologica” In this study, analysis of hair root status showed similar abnormalities in both primary and secondary syphilis patients, though it remains unclear if these are specific to syphilis.
3 citations
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May 2013 in “Journal of the American Association of Nurse Practitioners” This review evaluates six primary studies on androgenetic alopecia treatments and suggests topical minoxidil or finasteride as first-line options, recommending further research into treatments and practice guidelines.
3 citations
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January 1991 in “Toxicology in Vitro” This study reports that hair follicle cultures are effective for gap junctional intercellular communication studies and can be used to assess the tumor-promoting activity of certain environmental chemicals.
2 citations
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January 1974 in “Archives of Dermatological Research” Unknown factors significantly affect hair growth in skin grafts.