Effects of Estradiol on In Vitro Culture of Cashmere Goat Primary Hair Follicles

January 2009 in “ Anhui nongye kexue ”

Heng Li

estradiol 17 β-E2 hair follicles in vitro estrogen primary hair follicles

TLDR Higher estradiol levels slow cashmere goat hair follicle growth.

The study investigated the effects of estradiol on the growth and morphology of cashmere goat primary hair follicles in vitro. Hair follicles were cultured with varying concentrations of 17 β-E2 (0.1, 1.0, 10.0, 100.0 nmol/L). It was found that the growth rate at 0.1 nmol/L was similar to the control group, while higher concentrations (1.0, 10.0, and 100.0 nmol/L) inhibited hair follicle growth to varying degrees. Additionally, different concentrations led to distinct morphological changes in the hair follicles. This research provided a preliminary foundation for understanding how estradiol regulates the growth of cashmere goat hair follicles.

View this study on en.cnki.com.cn →

Discuss this study in the Community →

Related Community Posts Join

6 / 559 results

community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 9 upvotes 5 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community Regrowth after 9 months of DHT blockers, and 6 months of HRT

in Transgender 20 upvotes 1 month ago

A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

community What has helped you regrow your temples?

in Chat 21 upvotes 2 years ago

User seeks advice for regrowing temples, currently using Fin, oral Min, and dermarolling. Suggestions include improving scalp environment and considering RU58841 or dutasteride.

community Using Fin and Alfatradiol in conjunction?

in Finasteride/Dutasteride 5 upvotes 3 years ago

User considers adding Alfatradiol to their topical finasteride treatment for hair loss. Others discuss Alfatradiol as a weak estrogen and 5α-reductase inhibitor used for pattern hair loss in men and women.

community We need to keep these snake oil companies accountable.

in Treatment 120 upvotes 1 year ago

Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 1 year ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

Related Research

3 / 3 results

Evaluation of Melatonin and Bromocryptine Administration in Spanish Goats