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Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Certain RNA molecules are important for the development of wool follicles in sheep.

A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Computational tools identified 29 drugs that could potentially target 19 genes involved in chemotherapy-induced hair loss, which could lead to more effective treatments.

Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.

Using deep learning to predict gene expression from images could help assess colorectal cancer metastasis.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.

Neoadjuvant chemotherapy followed by surgery leads to fewer severe complications and better quality of life than immediate surgery in advanced ovarian cancer patients with high tumor load.

In the Jazan region of Saudi Arabia, hair loss is common, especially among women, older people, and those with higher education and BMI. Stress, poor nutrition, and hormonal changes are key causes, but many don't seek medical help.

People with Alopecia Areata have more herpes simplex infections but similar rates of cancer, blood clots, and heart disease compared to those without it.

Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.

More effective treatments are needed for severe alopecia areata.

Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.

The EVInews database provides significantly higher quality information than web-based sources for pharmacists.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

The 25Up study collected extensive data on mental disorders and related factors in Australian twins and siblings to investigate the genetics of psychiatric illnesses.

Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.

A rapid screening method using trichoscopy and clinical data can improve diagnosis and treatment of tinea capitis.

Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Certain natural biostimulants can increase lettuce yield and improve its nutritional content.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.