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This study indicates that sheep prenatally androgenized with testosterone show wool fiber diameter changes that parallel the increased hair diameter in women with polycystic ovary syndrome.

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.

This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.

In this study, prenatal androgen exposure was linked to altered sexual behaviors in both male and female mice, with specific effects on mounting and lordosis behaviors.

This study observed that both prenatal androgen exposure and postnatal early-life environment influence the development of PCOS-like phenotypes and changes in the gut microbiota in prenatally androgenized offspring.

This study found that women with PCOS were more likely to have longer anogenital distances, indicating possible intrauterine origins linked to prenatal androgen exposure.

This review discusses emerging concepts in PCOS from the AEPCOS 2010 meeting and reports no clinical findings; it suggests that the transition of care in congenital adrenal hyperplasia could inform PCOS adolescent care.

This study reported that prenatal exposure to dihydrotestosterone altered long-term androgen metabolism in juvenile male rats, suggesting different regulatory mechanisms for 5a-reductase in hypothalamic versus pituitary tissues.

This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.

This paper reviews the diagnostic criteria, associated morbidities, and possible evolutionary advantages of polycystic ovary syndrome, but does not report any new findings.

This paper discusses the link between polycystic ovarian syndrome (PCOS) and health issues like infertility and cardiovascular diseases, caused by both genetic and environmental factors, but reports no new clinical findings.

This review explores the hypothesis that polycystic ovary syndrome may originate in fetal life due to genetic predispositions and environmental influences, but it reports no new clinical findings.

This study found that LepRb neurons in the brain are important targets for androgen action and influence sex-specific differences in reproductive and metabolic regulation, implicating them in conditions such as polycystic ovary syndrome.

This article discusses the connection between prenatal androgen exposure, marked by the second-to-fourth digit ratio, and seborrheic dermatitis, but reports no new experimental findings.

This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.

In this study, researchers found that pregnant mice exposed to excessive androgen led to thinner ventricular walls and cardiac hypertrophy in offspring, suggesting that prenatal androgen exposure adversely affects cardiac health through reduced cardiomyocyte proliferation.

This review discusses the role of microglia in mediating prenatal androgen effects on the female brain, potentially contributing to PCOS development and neuroendocrine dysfunctions, but reports no new results.

This review discusses the hypotheses surrounding the developmental origins of polycystic ovary syndrome, particularly the role of prenatal androgen exposure, and reports no new experimental results.

This review summarizes the influence of gene polymorphisms on genetic predisposition to polycystic ovary syndrome, but reports no new experimental or clinical results.

This review discusses the early developmental origin of premature adrenarche and polycystic ovary syndrome and highlights potential utero-based mechanisms, reporting no new clinical findings.

This abstract reviews the characteristics and health risks associated with polycystic ovary syndrome and does not report new findings, highlighting the syndrome's multifactorial nature.

This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.

This study found that women with nonclassic congenital adrenal hyperplasia (NC-CAH) reported lower sexual function and higher sexual distress compared to those with classic CAH (C-CAH), particularly among those showing signs of androgen excess.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.

This chapter reviews genetic defects in female sexual differentiation, focusing on 46,XX disorders of sex development and the impact of genetic factors and sex steroids on development, but reports no new clinical findings.

This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

This article reviews polycystic ovary syndrome in adolescents, highlighting its endocrine and metabolic features, and reports no new clinical findings; the etiology may involve early-life abnormalities in androgen production.

This article discusses the complexities of diagnosing and managing polycystic ovary syndrome in adolescents and highlights the lack of established diagnostic criteria and unclear clinical implications, without presenting new clinical findings.