The Hair Loss Encyclopedia

Seasonality, Climatic Unpredictability, Food Deprivation, and Polycystic Ovary Syndrome

June 2008 in “ CRC Press eBooks ”

Polycystic Ovary Syndrome PCOS genetic predispositions evolutionary perspectives thrifty genotype hypothesis seasonality climatic unpredictability food scarcity

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TLDR PCOS may have evolved as an advantage in past environments with food scarcity.

The document explored the prevalence, genetic predispositions, and evolutionary perspectives of Polycystic Ovary Syndrome (PCOS), affecting about 1 in 12 females with significant interpopulation differences. It discussed genetic and developmental factors contributing to PCOS and suggested that PCOS might have been advantageous in past environments with food scarcity, aligning with the 'thrifty genotype' hypothesis. The document proposed that seasonality and climatic unpredictability might have influenced the evolutionary development of PCOS. It emphasized the need for further research to understand the genetic and environmental interactions influencing PCOS and improve treatment strategies beyond symptomatic relief.

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High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

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community PCOS Hair Loss: What’s Helped Me (and What Didn’t)

in Treatment 10 upvotes 6 months ago

OP shares their experience with PCOS-related hair loss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 56 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

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