30 citations,
November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
29 citations,
October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
29 citations,
February 2004 in “Experimental and Clinical Endocrinology & Diabetes” Men with early balding often have hormone levels similar to women with polycystic ovary syndrome.
26 citations,
June 2016 in “Pediatric Dermatology” Premature hair graying in young Turkish adults is more likely if they have stress, a family history of graying, drink alcohol, have chronic diseases, are older, or are taller.
26 citations,
October 2011 in “Biological trace element research” Low copper levels might cause premature graying of hair.
25 citations,
January 2013 in “International Journal of Trichology” Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.
20 citations,
January 2016 in “International journal of trichology” Young Indians with premature graying often have lower levels of certain nutrients and unhealthy lifestyles.
20 citations,
July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
16 citations,
January 2018 in “International journal of trichology” Genetics and nutritional deficiencies are key factors in premature graying of hair.
16 citations,
January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Low levels of vitamin B12 and ferritin are linked to early hair graying.
16 citations,
January 2013 in “Internal Medicine” Early hair whitening may indicate a higher risk of heart disease in young and middle-aged men.
14 citations,
April 2007 in “Journal of aging and health” Balding men had lower bone density, while balding women had higher hip bone density.
12 citations,
December 2005 in “PubMed” Some men with early hair loss may have similar hormonal changes to women with Polycystic ovary syndrome, and could be at risk for developing type 2 diabetes.
10 citations,
February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
7 citations,
July 2020 in “Dermatologic therapy” Premature graying of hair is linked to various health issues and can sometimes be reversed by treating underlying conditions.
7 citations,
June 2020 in “Experimental dermatology” Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.
7 citations,
December 2018 in “Journal of Cosmetic Dermatology” Eating vegetarian, having allergies, and family history might be linked to getting gray hair early.
6 citations,
December 2018 in “The American Journal of Dermatopathology” Early shedding of the inner root sheath in noninflamed hair follicles is a relatively specific sign of Central Centrifugal Cicatricial Alopecia.
5 citations,
January 2018 in “Acta dermato-venereologica” Premature hair greying may indicate a higher risk of metabolic problems.
5 citations,
March 2015 in “Clinical and Experimental Dermatology” Chemotherapy caused a woman's permanent hair loss and early menopause.
4 citations,
July 2019 in “IOP conference series” Most young men with early gray hair have low vitamin D but normal iron levels.
4 citations,
January 2016 in “Annals of dermatology/Annals of Dermatology” Iron supplements can restore normal hair color in cases of premature graying linked to iron deficiency.
3 citations,
March 2021 in “Cureus” A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
2 citations,
November 2017 in “International Journal of Research in Dermatology” Premature hair loss doesn't increase the risk of metabolic syndrome.
2 citations,
November 2017 in “Cardiovascular endocrinology” Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.
2 citations,
May 2017 in “Maturitas” Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
2 citations,
January 2017 in “Journal of Pigmentary Disorders” Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
1 citations,
January 2023 in “International Research Journal of Ayurveda & Yoga” Ayurveda suggests natural treatments for premature hair greying caused by an imbalance of Pitta dosha.
1 citations,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” Low zinc levels might contribute to early hair graying.