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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Cancer treatments often cause hair loss and damage, affecting patients' mental health.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Stem cell self-renewal is complex and needs more research for full understanding.

Targeting the skin's endocannabinoid system could help treat skin disorders.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Some women with PCOS have rare genetic variants linked to the condition.

Melatonin receptor genes likely play an important role in the development of goose feather follicles.

Melatonin may help treat PCOS symptoms in rats.

Exercise and finasteride together improve ovary health in PCOS rats.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.

Excess androgens may cause PCOS, not just be a symptom.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Different types of PCOS need specific diagnosis methods and treatments.

Surgery can be a safe and effective option for infertile women with PCOS who don't respond to medication and want to get pregnant.