research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
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research Knockout of mTOR/Akt Inhibitor REDD1 Results in Hair Cycle-Independent Dermal Adipose Expansion by Promoting Adipocyte Differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research The Wound Healing of Fractional Photothermolysis Mimics Scarless Healing with Minimal Myofibroblast Activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research The ATP-Dependent Chromatin Remodeler BRG1 Controls Epidermal Keratinocyte Migration During Human Cutaneous Wound Healing
BRG1 is essential for skin cells to move and heal wounds properly.
research SnapshotDx Quiz: April 2019
Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Therapeutic Updates on Lichen Planopilaris and Frontal Fibrosing Alopecia: A Systematic Review
Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.
research Frontal Fibrosing Alopecia: Clinical Features, Diagnosis, and Treatment Challenges
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Dermal White Adipose Tissue Enhances Proliferation, Pigmentation, and Hair Shaft Elongation in Human Hair Follicles Ex Vivo
Fat under the skin can help hair grow longer, darker, and increase cell growth.
research Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium
The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
research Skin Commensal Antigens: Taking the Road Less Traveled
Skin bacteria can help wound healing by activating certain immune cells.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Serum Markers of Thrombophilia in Pregnant Women with Systemic Lupus Erythematosus
Pregnant women with Systemic Lupus Erythematosus have a higher risk of blood clotting problems.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research The Abnormal Skin Structure of Newborn Wistar Rats Maternally Treated with Aspartame: Histological and Immunohistochemical Study
Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.
research Comparative Analysis of the Clinical-Pathological and Immunopathological Characteristics of Lichen Planopilaris and Frontal Fibrosing Alopecia
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
research Comparison of Androgenic Hormone Levels in Various Phenotypes of Polycystic Ovarian Syndrome in High School Girls Aged 14 to 18 Years
Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research Subject Index
The document lists various dermatology topics, treatments, and diagnostic methods.
research Alopecias
The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.
research Type 2 Diabetes, Metabolic Syndrome, and Lipid Metabolism
Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
research Possible Role of Autophagy Activation in Stimulation of Regeneration
The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.