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This study found that Sox2 within dermal papilla cells in the hair follicle regulates hair pigmentation, influencing the type and production of melanin.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

In this study, researchers found that overexpression of LncRNA RP11-818O24.3 in hair follicle stem cells promotes their proliferation, self-renewal, and differentiation while inhibiting apoptosis through the FGF2-mediated PI3K/AKT signaling pathway, suggesting potential therapeutic applications for hair loss treatment.

In this study, a risk score was developed and validated to identify patients at high risk of clinical failure after femoropopliteal peripheral vascular intervention, aiming to guide the selection of patients who may benefit from paclitaxel-coated devices or alternative strategies.

In this study, researchers found that in mouse models of alopecia areata, the expression of immune-regulating molecules PD-L1 and PD-L2 in dermal fibroblasts is increased by activated T cells, potentially indicating a lack of negative immune control in affected skin.

This study introduced a statistical method, PLACO, which revealed novel genetic regions associated with both Type 2 Diabetes and Prostate Cancer from GWAS data.

This study identifies mutations in the SRD5A3 gene as a cause of a new type of congenital disorder of glycosylation, impacting mental, ophthalmologic, and cerebellar functions.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

This study found that the PPAR-γ modulator N-acetyl-GED may enhance mitochondrial function in human hair follicles, particularly in outer root sheath keratinocytes.

In this study, researchers found that thrombin may influence cyclic hair growth through its receptor PAR-1, although it does not seem to stimulate dermal papilla cell proliferation physiologically.

This study reported that CYP21A2 heterozygous mutations do not significantly contribute to the pathogenesis of polycystic ovary syndrome.

This study found that overexpression of PTHrP in mice chondrocytes led to short-limbed dwarfism and delays in endochondral ossification, highlighting PTHrP's role in inhibiting chondrocyte differentiation.

This study developed mathematical models to simulate phosphate uptake in rice and Arabidopsis, suggesting a phosphate-sensitive repressor could regulate PHO2 mRNA levels, and highlighting potential targets and traits for improving phosphorus-use efficiency.

This study found that platelet factor 4 in platelet-rich plasma suppresses human hair follicle growth and alters related gene expressions, suggesting potential implications for its use in hair loss treatment.

This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.

Mycophenolic acid may help hair grow by activating pathways important for hair growth.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

In this study, the researchers found that optic atrophy 1 (OPA1) is involved in the transition between filamentous and rounded mitochondria in hair follicle dermal papilla cells, potentially influencing cellular energy dynamics.

This study showed that treating mouse fibroblasts with TTNPB can efficiently convert them into dermal-papilla-cell-like cells with strong hair-inducing capacity, suggesting potential for hair follicle regeneration therapies.

The study found that silencing the gene p16INK4a in dermal papilla cells promotes their growth and aggregative behavior, suggesting a potential therapeutic target for androgenetic alopecia.

In this study, researchers demonstrated that the Id2 gene acts as a direct target and effector of BMP signaling, playing a key role in maintaining quiescence in hair follicle stem cells in vivo.

In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.

This case report describes a 32-year-old man who developed SCC of the common bile duct a year after receiving treatment for a malignant proliferating trichilemmal tumour on the scalp.

This study found no association between the -866G/A polymorphism in the UCP2 gene and the development of polycystic ovary syndrome.

This study found that higher baseline expression of SRD5A2 in prostate tissue was associated with a better response to finasteride in men with benign prostatic hyperplasia.

This study found that TCF7L2 gene polymorphism is linked to alopecia areata, but no significant difference in treatment outcomes was observed between PRP and conventional therapy among different genotypes.

This study reported variable expression levels of TRα and CRABPII genes during the prenatal development of cashmere goats, contributing to an understanding of hair follicle formation in these animals.