Expression Patterns of TRα and CRABPII Genes in Chinese Cashmere Goat Skin During Prenatal Development

August 2015 in “ Han'gug dongmul jawon gwahag hoeji/Han-guk dongmul jawon gwahak hoeji/Journal of animal science and technology ”

Tao Zhong, Wei Zhao, Z. Y. Zhou, L i Li, Linjie Wang, Hua Li, Hongping Zhang

TRα CRABPII real-time quantitative PCR RT-qPCR mRNA gene expression embryonic development fetal skin thyroid hormone receptor alpha cellular retinoic acid-binding protein II PCR messenger RNA gene activity embryo development skin development

TLDR TRα and CRABPII genes change their activity levels during goat fetal skin development.

The study investigated the expression patterns of TRα and CRABPII genes in the fetal skin of Chinese cashmere goats during prenatal development using real-time quantitative PCR (RT-qPCR). TRα was expressed at high levels at embryonic day (E) 70, decreased slightly from E75 to E90, and peaked at E130. CRABPII mRNA showed an 'up-down-up' trend, with the highest expression at E75, a significant down-regulation from E80 to E120, and a mild increase at E130. These findings provided insights into the dynamic expression of these genes during cashmere formation, potentially informing further studies on their roles in regulating cashmere growth in goats.

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TRα and CRABPII genes change their activity levels during goat fetal skin development.