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Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sulforaphane from broccoli can help protect skin from sun damage.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Certain drugs that block specific enzymes can help treat prostate diseases.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

CIP/KIP proteins help stop cell division and support hair growth.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Mutations in certain receptors can cause diseases and offer new treatment options.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.