January 2021 in “Asian Journal of Pharmaceutical and Clinical Research” FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.
9 citations,
October 2012 in “Thermochimica Acta” Finasteride's two forms have different stability based on temperature and pressure.
2 citations,
October 2004 in “Organic Process Research & Development” The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
August 2014 in “Acta Crystallographica” Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.
66 citations,
February 2010 in “CrystEngComm” Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
47 citations,
August 2014 in “The Journal of Clinical Endocrinology and Metabolism” The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.
23 citations,
March 2019 in “Environmental Chemistry Letters” Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
22 citations,
April 2000 in “International Journal of Dermatology” A 78-year-old farmer with lung disease had skin lesions from a fungal infection that healed completely with medication.
18 citations,
September 1990 in “Veterinary Dermatology” Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.
16 citations,
November 2015 in “Journal of Molecular Structure” Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.
13 citations,
February 2015 in “Journal of Pharmaceutical Sciences” Three finasteride forms exist; "form X" doesn't.
10 citations,
February 2015 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
2 citations,
February 2013 in “Journal of The American Academy of Dermatology” Platelet-rich plasma may improve hair density in androgenetic alopecia patients.
Cross-section trichometry is an accurate method to measure hair loss and growth.
February 2013 in “Journal of the American Academy of Dermatology” Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.
February 2013 in “Journal of the American Academy of Dermatology” Certain gene variations might increase the risk of a hair loss condition in Koreans.
January 1989 in “Journal of The American Academy of Dermatology” Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
January 1989 in “Journal of The American Academy of Dermatology” Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
188 citations,
October 2012 in “The AAPS Journal” The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
165 citations,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
119 citations,
October 1992 in “Fundamental & Clinical Pharmacology” Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
105 citations,
January 2004 in “The Journal of Urology” Finasteride improves chronic pelvic pain, saw palmetto doesn't.
52 citations,
March 1979 in “Toxicology and Applied Pharmacology” Minoxidil can cause heart muscle damage in dogs.
51 citations,
October 1981 in “British Journal of Dermatology” Some patients developed skin inflammation after obesity surgery, and a medication called dapsone helped treat it.
44 citations,
March 1991 in “International Journal of Dermatology” Prompt treatment of inflammatory tinea capitis (kerion) is crucial to prevent scarring and hair loss.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
37 citations,
November 2003 in “Veterinary pathology” Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
25 citations,
January 2005 in “Pediatric Dermatology” Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
25 citations,
July 1991 in “International Journal of Dermatology” Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.