research Drug Polymorphism Identification Using Fourier Transform-Raman Spectroscopy: A Comparative Study of Lamivudine and Finasteride Drugs
FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.
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research Phenomenology of Polymorphism: The Topological Pressure–Temperature Phase Relationships of the Dimorphism of Finasteride
Finasteride's two forms have different stability based on temperature and pressure.
research A Review of U.S. Patents in the Field of Organic Process Development Published During July and August 2004
The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
research Evaluation of Polymorphism Influence in Finasteride
Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.
research Attempted Construction of Minoxidil: Carboxylic Acid Cocrystals; 7 Salts and 1 Cocrystal Resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research The Polycystic Ovary Syndrome Evolutionary Paradox: A Genome-Wide Association Studies-Based, In Silico, Evolutionary Explanation
The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.
research Applications of Steroid Drugs Entrapped in Cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Cutaneous Alternariosis in a Patient with Idiopathic Pulmonary Fibrosis
A 78-year-old farmer with lung disease had skin lesions from a fungal infection that healed completely with medication.
research The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus
Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.
research Investigation of Intermolecular Interactions in Finasteride Drug Crystals in View of X-ray and Hirshfeld Surface Analysis
Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms: Does Form X Exist?
Three finasteride forms exist; "form X" doesn't.
research Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Autologous Platelet-Rich Plasma as a Potential Therapeutic Tool in Androgenetic Alopecia
Platelet-rich plasma may improve hair density in androgenetic alopecia patients.
research Cross-Section Trichometry: A Clinical Tool for Assessing the Progression and Treatment Response of Alopecia
Cross-section trichometry is an accurate method to measure hair loss and growth.
research Becker Nevus of the Face with Asymmetrical Growth of Beard Hair
Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.
research Association Between Epidermal Growth Factor and Epidermal Growth Factor Receptor Gene Polymorphisms and Susceptibility to Alopecia Areata in Korean Population
Certain gene variations might increase the risk of a hair loss condition in Koreans.
research Reply
Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
research Chemotaxis in Psoriasis
Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing
The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
research Review of Pharmacological Effects of Myrtus Communis L. and Its Active Constituents
Myrtle has various health benefits and potential for medicine development.
research Potassium Channel Openers: Pharmacological and Clinical Aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome
Finasteride improves chronic pelvic pain, saw palmetto doesn't.
research Acute Cardiomyopathy Induced by the Vasodilating Antihypertensive Agent Minoxidil
Minoxidil can cause heart muscle damage in dogs.
research The Spectrum of Inflammatory Skin Disease Following Jejuno-Ileal Bypass for Morbid Obesity
Some patients developed skin inflammation after obesity surgery, and a medication called dapsone helped treat it.
research Inflammatory Tinea Capitis (Kerion) Mimicking Dissecting Cellulitis
Prompt treatment of inflammatory tinea capitis (kerion) is crucial to prevent scarring and hair loss.
research Toxicological Studies with the Hypotensive Agent Minoxidil
Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
research Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-Mediated Root Sheath Disruption in Advance of Overt Hair Loss
Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
research A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine
A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
research Methotrexate for Generalized Pustular Psoriasis in a 2-Year-Old Child
Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
research Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.