Reply

    January 1989 in “ Journal of The American Academy of Dermatology ”
    Elise A. Olsen
    Image of study
    TLDR Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
    In the document, Dr. Joseph L. Jorizzo expresses skepticism about the long-term effectiveness of minoxidil for androgenic alopecia and tretinoin for aging skin, citing concerns about the potential for a credibility gap between dermatologists and patients due to high public expectations fueled by media hype. Dr. Elise A. Olsen responds by acknowledging the challenges in study designs for these medications but defends their validity, noting the statistically significant increase in hair growth with minoxidil and the efficacy of tretinoin despite difficulties in conducting double-blind trials. Olsen emphasizes the importance of dermatologists managing expectations through public education and views these medications as promising prototypes that can be improved upon. Additionally, the document mentions a study on monocyte and neutrophil chemotaxis in psoriasis, with varying results depending on the techniques used, suggesting that the "leading-front" method may not be suitable for demonstrating enhanced chemotactic response in psoriatic phagocytes.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes 2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 1 year ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 10 months ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Warning: Danish Nordic Hair Growth is scam!

      in Product  86 upvotes 1 year ago
      A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenic alopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinical trial.

    Similar Research

    5 / 1000+ results