2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” This article reviews the need for multicenter clinical trials to establish reference data for ultrasound screening protocols for Down syndrome and reports no new findings.
29 citations
,
July 1991 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Glycoproteins are present in the cell membranes of various keratin fibers.
10 citations
,
August 2020 in “Drug metabolism and drug interactions” This case series found that patients with the NUDT15 415C>T variant experienced severe azathioprine toxicity, suggesting genotype-based dosing could reduce adverse effects.
36 citations
,
June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
36 citations
,
January 2018 in “Scientific reports” This study observed that dietary intake of glucoraphanin during juvenile and adolescent stages prevented cognitive deficits and abnormal gene expressions in the brain of adult offspring exposed to maternal immune activation, potentially implicating centrosome-related genes in the development of psychosis.
54 citations
,
November 1998 in “Archives of dermatology” This article discusses the potential role of nutritional ingredients, such as thiols and tannins, in triggering pemphigus, and reports no new empirical findings.
9 citations
,
February 2012 in “Clinical Neurology and Neurosurgery” In this paper, three APS patients were followed over time, showing that the diagnosis and course of autoimmune polyglandular syndrome can evolve, highlighting the need for careful monitoring and potential re-evaluation.
59 citations
,
July 1972 in “Biochemistry” This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.
22 citations
,
October 2019 in “International Journal of Nanomedicine” This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.
1 citations
,
June 2015 in “Journal of anatomy” This study reported that novel kainate derivatives, especially ZCZ90, maintained potency in affecting proprioceptive sensory organ firing, aiding future receptor studies for potential treatment innovations.
March 2016 in “The Korean Society of Beauty and Art” This study found that using a hair-hardener improved hair thickness, amino acid content, surface condition, tensile strength, and wave efficiency without causing any allergic reactions in participants.
62 citations
,
December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that enzymatic conversion of Arg-51 in S100A3 protein to citrulline promotes homotetramer assembly, potentially increasing Ca²⁺ binding required for hair cuticular barrier formation.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.
20 citations
,
December 1999 in “Journal of Investigative Dermatology” Mutations in the hHb6 gene cause the hair disorder monilethrix.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports a novel geometric medicine solution, N‑K GM SERIES, claiming to eliminate aflatoxin, offer a universal cancer cure, and provide numerous health benefits, including increased life expectancy, with deployment focused on the "Aflatoxin Belt" regions like Sudan.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This publication presents a library of precision geometric medicines that reportedly kill harmful bacteria and fungi while sparing beneficial organisms, using a delivery system that targets pathogens specifically and avoids ecological harm.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that tissue transglutaminase (TG2) may play a role in sebum production by regulating autophagy in sebaceous glands, offering potential targets for dermatological interventions.
35 citations
,
August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
2 citations
,
September 2021 in “F1000Research” This study found that the ABCG2 (Q191K) polymorphism increases the risk of hyperuricemia and hypercholesterolemia specifically in young Mexican males.
32 citations
,
January 2000 in “Human Heredity” This study found that the mutation Glu402Lys in keratin hHb6 may be associated with monilethrix, and homozygous patients in a consanguineous family exhibited more severe symptoms.
86 citations
,
February 2009 in “Journal of Neuroscience” This study found that during late pregnancy in rats, there is an increase in extrasynaptic GABA A receptor number in granule cells of the dentate gyrus, linked to hormonal fluctuations.
135 citations
,
October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that exogenous glutamic acid promoted hair growth and keratinocyte proliferation, indicating a potential new signaling pathway in the skin.
15 citations
,
October 1970 in “Archives of disease in childhood” Hair amino acid levels can indicate metabolic disorders.
In this study, researchers found that during late pregnancy, neuroactive steroid fluctuations increase the number of extrasynaptic GABAA receptors in rat hippocampal cells.
1 citations
,
March 2012 in “Revue neurologique” This study reports that both a 9-month-old with phenylketonuria on a phenylalanine-free diet and mice on a deficient diet exhibited severe health issues, highlighting the need for cautious dietary management.
April 2015 in “Andrology” This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.
3 citations
,
September 2025 in “ChemMedChem” This review highlights the inadequacy of the "specificity paradigm" in drug design for complex diseases like Alzheimer's and cancer, suggesting a shift toward developing multitarget drugs to improve treatment efficacy by interacting with multiple targets through various mechanisms.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a novel geometric medicine approach, utilizing the N-K Universal Computer, was reported to eliminate aflatoxin contamination and significantly reduce cancer rates across the "Aflatoxin Belt" through precision targeting of harmful fungi while preserving ecological balance, without observed toxicity or resistance.
84 citations
,
December 2018 in “Genetics in Medicine” This article reviews evidence- and consensus-based recommendations for using pegvaliase in adults with PKU and reports no new clinical results.