TLDR Avoiding certain nutrients and drugs may help manage pemphigus.
Individuals genetically predisposed to pemphigus developed the disease only when additional factors were present, though these factors were unknown. Certain drugs (penicillamine, captopril, and rifampicin) were recognized as triggers. The study suggested that some nutrients with similar chemical compositions to these drugs might also act as triggers. Nutritional factors, including components found in fruit, leaves, roots, seeds, and water, were suspected. Potential causative candidates included thiol, thiocyanate, phenols, and tannins. Eliminating these inciting ingredients could be crucial for managing the disease.
11 citations,
June 2011 in “Expert Review of Dermatology” Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
13 citations,
March 2019 in “Pharmacology Research & Perspectives” In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
4 citations,
January 2012 in “Chemical Immunology” Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
August 2023 in “JOJ dermatology & cosmetics” Antibiotics often cause skin reactions, making them a major health concern.
