14 citations
,
October 2016 in “Psychoneuroendocrinology” This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.
223 citations
,
January 2000 in “BioFactors” This study reports that bioactive peptides derived from food proteins may lower serum cholesterol and exhibit antihypertensive and immunostimulating effects, suggesting potential in preventing lifestyle-related diseases.
17 citations
,
October 2016 in “Artificial Cells Nanomedicine and Biotechnology” This study found that arginine-loaded lipidic nanoparticles improved hair follicle growth in male hamsters more effectively than an aqueous arginine solution.
64 citations
,
March 2004 in “Journal of Clinical Investigation” This study found that inhibiting the enzyme ornithine decarboxylase (ODC) prevented UVB-induced basal cell carcinomas in a mouse model, suggesting ODC is a potential target for chemoprevention strategies.
8 citations
,
June 1981 in “Clinica Chimica Acta” 6 citations
,
June 1976 in “Journal of Investigative Dermatology”
42 citations
,
February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that PNU 157706 is a highly potent inhibitor of human 5α-reductase enzymes, showing a stronger and longer-lasting antiprostatic effect in rats compared to finasteride.
43 citations
,
March 1942 in “The Journal of experimental medicine/The journal of experimental medicine” This study found that mice can synthesize inositol, but this ability is impaired when pantothenic acid is lacking in their diet.
2 citations
,
January 2011 in “Feed Review” This study found that weanling pigs fed a diet supplemented with 0.029% iron glycine chelate showed improved growth performance and better hair color compared to those receiving ferrous sulfide.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.
34 citations
,
October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”
March 2018 in “International Pharmacy Acta” This study concluded that niosomes could effectively serve as stable carriers for topical aminexil delivery, showing promising stability and a slow, biphasic release profile in laboratory settings.
2 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.
January 2016 in “Graduate Medical Education Research Journal” This study identified AH01 derivatives and related compounds with high antischistosomal efficacy and reduced antiandrogenic effects, suggesting potential new directions for schistosomiasis drug development.
January 2009 in “Xiandai huagong” This research outlines a chemical synthesis process for Finasteride, detailing the conversion of pregnadienolone acetate through various chemical reactions and modifications.
110 citations
,
January 1995 in “European Journal of Neuroscience” This study found that glycinergic synapses in the rat spinal cord are predominantly associated with gephyrin, though gephyrin may also be present at non-glycinergic synapses.
513 citations
,
February 2022 in “Advanced Science” This study demonstrated that incorporating PDA@Ag nanoparticles into a cationic guar gum hydrogel significantly enhanced photothermal conversion efficiency, achieving superior antibacterial efficacy both in vitro and in vivo, advancing the potential of PDA as a photothermal antibacterial agent.
This paper provides a comprehensive list of drugs including Ethamolin, Placidyl, Trecator-SC, Zarontin, Peganone, Didronel, and Lodine, detailing their indications, potential interactions, and reported adverse skin reactions, but it presents no new research findings.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
8 citations
,
January 2017 in “Environmental monitoring and assessment” Hair from different ethnic groups affects soil nutrient release differently.
12 citations
,
March 2018 in “Analytical chemistry” This study found that a new analytical approach revealed an increased brain pregnenolone level following finasteride treatment in a mouse model, suggesting potential for improved understanding of neurosteroid roles in brain excitability.
10 citations
,
February 2013 in “PLoS ONE” This study found that neprilysin (NEP) activity and expression play a significant role in regulating the hair cycle in rats, with a specific inhibitor suppressing hair growth in mice.
20 citations
,
February 2017 in “European journal of pharmaceutical sciences” This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.
8 citations
,
November 1976 in “Journal of Investigative Dermatology” 5 citations
,
February 1998 in “Polymer” Human hair keratin has a 40% α-helix structure that changes to a random coil in 8 M urea.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
36 citations
,
July 1988 in “Archives of Dermatological Research” Pili annulati is caused by a protein metabolism disorder affecting hair structure.
49 citations
,
September 2004 in “Journal of the European Academy of Dermatology and Venereology” This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.
20 citations
,
February 1968 in “Journal of Histochemistry & Cytochemistry” This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.