Bioactive Peptides Derived from Food Proteins Preventing Lifestyle-Related Diseases

    January 2000 in “ BioFactors ”
    Masaaki Yoshikawa, Hiroyuki Fujita, Nobuyuki Matoba, Yasuyuki Takenaka, Taichi Yamamoto, Rena Yamauchi, Hirotaka Tsuruki, Kyoya Takahata
    TLDR Food-derived peptides may help prevent diseases like high blood pressure and high cholesterol, and can support the immune system.
    Bioactive peptides derived from food proteins have been found to have potential in preventing lifestyle-related diseases. These peptides, released after enzymatic digestion, include inhibitory peptides for angiotensin I-converting enzyme (ACE) with anti-hypertensive effects, such as LKPNM from dried bonito, which is activated by ACE and has a prolonged effect post-oral administration. Additionally, vasorelaxing peptides like ovokinin and ovokinin(2-7) from ovalbumin digests have shown antihypertensive effects when taken orally. Research also indicated that low molecular weight peptides from food proteins can lower serum cholesterol without increasing cholesterol and bile acid excretion. Furthermore, an immunostimulating peptide from soybean protein digest was found to prevent chemotherapy-induced alopecia.
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