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    Glossary Polarity

    distribution of electrical charge or structural orientation within molecules

    Polarity refers to the distribution of electrical charge over the atoms joined by a bond. In the context of biology and hair, it can describe the orientation and structural differences within cells or molecules, such as the way hair follicles have distinct regions that influence hair growth direction and type. This concept is crucial for understanding cellular functions and interactions, as well as the mechanisms behind hair development and disorders like alopecia.

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    1. Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity Nature Communications · 2019 · 38 citations
    2. Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance 2016 · 26 citations
    3. Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling EMBO journal · 2021 · 5 citations
    4. A CASE REPORT OF ALOPECIA AREATA TREATED WITH CALCAREA CARBONICA BY USING POLARITY ANALYSIS METHOD INDIAN JOURNAL OF APPLIED RESEARCH · 2024
    5. Barley disease susceptibility factor RACB acts in epidermal cell polarity and positioning of the nucleus Journal of experimental botany · 2016 · 41 citations
    6. Epidermal Polarity Genes in Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 32 citations
    7. Responses of hair follicle–associated structures to loss of planar cell polarity signaling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 29 citations
    8. Partial interchangeability of <i>Fz3</i> and <i>Fz6</i> in tissue polarity signaling for epithelial orientation and axon growth and guidance Development · 2014 · 28 citations
    9. ILK modulates epithelial polarity and matrix formation in hair follicles Molecular biology of the cell · 2013 · 22 citations
    10. Region-specific reversal of epidermal planar polarity in the <i>rosette</i> fancy mouse Development · 2023 · 2 citations
    11. The high-polarity fraction of tail fat derived from Lanzhou Fat-Tailed sheep enhances skin wound healing through the regulation of inflammatory factors and the TGF-β1/Smad3 signaling pathway Food Science and Human Wellness · 2026
    12. The Role of Cell Polarity Regulator aPKC in Hair Follicle Stem Cell Maintenance and Wound Healing Nihon Ika Daigaku Igakkai Zasshi · 2020
    13. Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse Journal of Investigative Dermatology · 2009 · 92 citations
    14. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns Developmental Biology · 2017 · 33 citations
    15. Functional redundancy of <i>Frizzled 3</i> and <i>Frizzled 6</i> in planar cell polarity control of mouse hair follicles Development · 2018 · 24 citations
    16. Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Cell death and differentiation · 2012 · 19 citations
    17. Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity Journal of cell science · 2017 · 11 citations
    18. Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity Frontiers in cell and developmental biology · 2023 · 7 citations
    19. Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development Development · 2022 · 7 citations
    20. 236 Wnt/planar cell polarity impairment and the genetics of yellow nail syndrome Journal of Investigative Dermatology · 2024
    21. 851 The role of astrotactin2 in regulating mammalian skin polarity 2017
    22. A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration Journal of Dermatological Science · 2016
    23. Root hair growth in Arabidopsis thaliana is directed by calcium and an endogenous polarity Planta · 1997 · 200 citations
    24. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    25. AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity The Plant Journal · 2011 · 56 citations
    26. Human hair follicle: reservoir function and selective targeting British Journal of Dermatology · 2011 · 97 citations
    27. High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis Journal of pharmaceutical and biomedical analysis · 2017 · 49 citations
    28. Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide: Measurement and Correlation Journal of Chemical & Engineering Data · 2009 · 19 citations
    29. Secondary ion mass spectrometric investigation of penetration of coconut and mineral oils into human hair fibers: relevance to hair damage. PubMed · 2001 · 11 citations
    30. Human Hair: An Important Biological Matrix of Interest Advances in pharmacology and clinical trials · 2023