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    Glossary Planar Cell Polarity

    coordinated orientation of cells within tissue plane

    Planar Cell Polarity (PCP) refers to the coordinated orientation of cells along a tissue plane, rather than just up and down. This is crucial for various biological processes, such as the uniform direction of hair growth on the skin or the proper alignment of cells in the inner ear for hearing.

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    1. Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse Journal of Investigative Dermatology · 2009 · 92 citations
    2. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns Developmental Biology · 2017 · 33 citations
    3. Responses of hair follicle–associated structures to loss of planar cell polarity signaling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 29 citations
    4. Functional redundancy of <i>Frizzled 3</i> and <i>Frizzled 6</i> in planar cell polarity control of mouse hair follicles Development · 2018 · 24 citations
    5. Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Cell death and differentiation · 2012 · 19 citations
    6. Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity Frontiers in cell and developmental biology · 2023 · 7 citations
    7. 236 Wnt/planar cell polarity impairment and the genetics of yellow nail syndrome Journal of Investigative Dermatology · 2024
    8. Region-specific reversal of epidermal planar polarity in the <i>rosette</i> fancy mouse Development · 2023 · 2 citations
    9. Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development Development · 2022 · 7 citations
    10. 851 The role of astrotactin2 in regulating mammalian skin polarity 2017
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