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Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Significant progress was made in understanding PXE, but effective treatments are still needed.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.

Neutrophils are important for causing chronic itch in atopic dermatitis, and blocking the CXCR3 receptor may reduce this itch.

Personalized treatments for hair loss are becoming more effective by using genetic information.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

A gene mutation in Lama3 is linked to a common type of hair loss.

Boron deficiency in maize affects leaf boron levels and nutrient uptake differently depending on root hair presence and soil type.

Hair follicle sampling is a practical method for measuring biomarkers in children with and without Fragile X syndrome.

Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.

Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Non-coding RNAs could help detect and treat radiation damage.

A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.

cDermo-1 causes dense skin, feathers, and scales in chickens.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Adding a second method to PROTACs could improve cancer treatment.