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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Sulforaphane from broccoli can help protect skin from sun damage.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Liposomes could improve how skin care products work but are costly and not very stable.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Finasteride improves chronic pelvic pain, saw palmetto doesn't.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Improving skin barrier and using antifungal treatments can help manage dandruff.

A wearable device using electric stimulation can significantly improve hair growth.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.