Expression of COX-2 and Bcl-2 in 50 Patients of Lichen Planus
April 2020
in “
International journal of clinical and diagnostic pathology
”
Studysummary This study examined Bcl-2 and COX-2 expression in Lichen Planus cases, highlighting their roles in apoptosis protection and inflammation, with results analyzed statistically. Our plain-language summary of this paper — not a Tressless recommendation.
In the study conducted on 50 clinically and histopathologically confirmed cases of Lichen Planus, researchers investigated the expression of Bcl-2, a protein that plays a significant role in protecting cells from apoptosis (programmed cell death), and COX-2, an enzyme that is involved in inflammation, tumor growth, invasion, and the inhibition of apoptosis. The expression levels of these proteins were examined using immunohistochemical staining techniques. The collected data were then statistically analyzed to understand the involvement of these proteins in Lichen Planus.
