219 citations
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March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
180 citations
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November 1991 in “American Journal of Psychiatry” This study found that fluoxetine did not demonstrate short-term efficacy in treating trichotillomania in a placebo-controlled, double-blind crossover setting.
141 citations
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February 2005 in “Journal of the American Academy of Dermatology” In this study, oral prednisolone pulse therapy led to significant hair regrowth in some patients with extensive alopecia areata, whereas no improvement was seen in the placebo group.
92 citations
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June 2010 in “Journal of The American Academy of Dermatology” This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.
18 citations
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November 2016 in “International clinical psychopharmacology” This study found that in a 10-week trial, inositol did not significantly reduce trichotillomania symptoms compared to placebo, although 42.1% of inositol-treated patients felt 'much or very much improved' at the study's end.
17 citations
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July 1988 in “International Journal of Dermatology” In this study, 2% minoxidil solution was found to be a safe and more effective treatment for early male pattern baldness compared to placebo.
13 citations
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November 2013 in “The Journal of Dermatology” This study suggests that minoxidil 2% lotion is a safe and effective treatment for enhancing eyebrows, showing better results than placebo after 16 weeks.
10 citations
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May 2007 in “PubMed” This study found that 1% topical minoxidil significantly increased hair count and improved hair growth perception among Japanese women with androgenetic alopecia compared to placebo.
7 citations
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December 2020 in “Dermatologic Therapy” In this study, intradermal injections of 0.5% minoxidil significantly improved hair growth and volume in women with female androgenetic alopecia compared to a placebo, with a good safety profile reported.
6 citations
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June 2021 in “EClinicalMedicine” In this study, ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported.
5 citations
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November 2024 in “Frontiers in Nutrition” In this randomized controlled trial, oral intake of the probiotic Latilactobacillus curvatus LB-P9 significantly improved hair luster, elasticity, and participant satisfaction in individuals with mild to moderate hair damage compared to placebo, without significant adverse effects reported.
5 citations
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January 2020 in “Skin Research and Technology” This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.
5 citations
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January 2018 in “Skin Pharmacology and Physiology” This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.
5 citations
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November 2016 in “Experimental and Therapeutic Medicine” In this study, BeauTop treatment significantly increased hair growth in people with androgenetic alopecia compared to placebo, showing effectiveness without adverse reactions.
4 citations
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August 2022 in “Aesthetic Surgery Journal” This study found that one session of intradermal botulinum toxin type A injection decreased scalp sebum secretion and perception of greasiness more effectively than saline for up to 3 months.
3 citations
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September 2022 in “Veterinary Dermatology” This study found that 18 mg melatonin implants did not significantly prevent recurrence of canine flank alopecia compared to placebo in dogs, though the treatment was well-tolerated, with no evidence of improved efficacy.
3 citations
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September 2021 in “EClinicalMedicine” In this study, ALRV5XR treatment significantly increased terminal hair density in men with androgenetic alopecia after 24 weeks, while also decreasing vellus hair density, and was well tolerated without adverse events, suggesting its potential efficacy over standard therapies.
2 citations
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October 2023 in “Cosmetics” This study found that applying 0.005% latanoprost topically to eyelashes significantly increased their length and darkened their color in healthy volunteers over three months, without causing any side effects or changes in intraocular pressure compared to a placebo.
1 citations
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May 2017 in “Journal of The American Academy of Dermatology” The moisturizer with phytol improved skin texture and reduced fine wrinkles better than the moisturizer without it.
May 2026 in “Journal of the American Academy of Dermatology” In this study, sublingual minoxidil was found to be a safe and effective treatment for increasing hair growth in transgender individuals with mild androgenetic alopecia who are undergoing full-dose testosterone therapy.
In this study, researchers developed vegan exosome-like vesicles from microalgae that mimic mammalian exosomes, demonstrating promising in vitro, ex vivo, and clinical effects such as improved wrinkle depth and elasticity, making them a potential alternative in cosmetic applications.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” In this randomized, placebo-controlled study, Kūlaris supplementation significantly improved quality of life for participants with mild-to-severe acne over 12 weeks, though no significant changes in general skin health measures were observed compared to placebo.
September 2025 in “Journal of the American Academy of Dermatology” Sublingual minoxidil significantly improves hair growth in transgender individuals on testosterone therapy.
April 2025 in “Cosmetics” In this randomized, double-blind study, a shampoo containing Plantago asiatica L. significantly improved hair thickness and density while reducing hair loss over 12 weeks in adults compared to a placebo.
August 2026 in “International Journal of Stem Cells” In this study, Korean adults with damaged hair who took 3g/day of low-molecular-weight collagen peptide GT for 24 weeks showed significant improvements in hair gloss, elasticity, and scalp elasticity compared to placebo, without any adverse events.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, UPA at doses of 15 mg and 30 mg showed higher efficacy than placebo for treating severe alopecia areata in adults and adolescents over 24 weeks, with a safety profile similar to approved uses.
October 2025 in “Acta Dermato Venereologica” Spontaneous hair regrowth in alopecia areata is possible but varies greatly among individuals.
July 2025 in “Journal of Investigative Dermatology” In this study, AMP-303 injections demonstrated a trend toward increasing non-vellus hair count in men with mild to moderate androgenetic alopecia, notably showing a 14.5% peak increase at 60 days compared to saline, with effects lasting up to five months.
January 2018 in “Figshare” This study found that a high-sesquiterpene extract from Curcuma aeruginosa slowed axillary hair growth in women by 22% compared to placebo over 12 weeks, with results delayed by 6 weeks, and participants reported satisfaction without adverse effects.
December 2022 in “Journal of Dermatology Research” This study found that Platelet Rich Plasma injection improved hair growth in women with Female Pattern Hair Loss compared to placebo, but larger trials are needed to validate these results.