The Effect of Sublingual Minoxidil on Androgenetic Alopecia in Transgender Individuals Receiving Testosterone for Gender-Affirmation: A 24-Week Single-Centre Double-Blinded, Randomized, Placebo-Controlled Clinical Trial

September 2025 in “ Journal of the American Academy of Dermatology ”

Gia Toan Tang, Shalem Leemaqz, Bevin Bhoyrul, Samantha Eisman, Rodney Sinclair, Ada S. Cheung

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research Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia

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research Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit?

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Using more than 5% minoxidil can help hair growth more, but results vary and side effects may increase.

research Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes

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Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

research The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years

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Minoxidil effectively stimulates hair growth in androgenetic alopecia.

Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial

research Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial

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A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Androgenetic Alopecia: Treatment Results with Topical Minoxidil

39 citations , March 1987 in “Journal of The American Academy of Dermatology”

Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.

research Topical Minoxidil Therapy and Hair Regrowth

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Minoxidil helps hair regrowth, especially with more indeterminate hairs.