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This study found that TPA induces apoptosis in pig renal epithelial cells by affecting cell cycle proteins, and activated ras can prevent this process.

This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.

This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.

This study found that the polyurethane-cellulose acetate scaffold containing plasma rich in growth factors enhanced gene expression linked to wound healing compared to controls.

In this study, researchers noted that while Poly-L-lactic acid dermal fillers boost collagen synthesis to add volume and reduce wrinkles, there is no established link between these fillers and hair loss according to existing literature.

This review discusses the potential therapeutic applications of platelet-rich plasma across several medical fields and reports a lack of standardized protocols and controlled trials to confirm its effectiveness.

This review discusses the efficacy and safety of platelet-rich plasma for facial rejuvenation but reports no definitive clinical results, noting the evidence remains insufficient for firm conclusions.

This review discusses the biological mechanisms, preparation techniques, and clinical applications of platelet-rich plasma therapy, highlighting its variable outcomes and potential improvements for efficacy and standardization; it reports no new clinical results.

This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.

This study found that NGAL expression increased in calcium-induced keratinocyte differentiation in vitro and was highly elevated in psoriasis-like skin conditions and skin cancers, suggesting a role in skin hyperplasia and homeostasis.

This review discusses the role of phospholipases in skin and hair health, suggesting that understanding their molecular control could inform new treatments for related conditions, but it presents no new clinical results.

In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.

This study found that treprostinil, a prostacyclin analog, significantly delayed fibroblast migration from healthy donors but did not affect fibroblast migration derived from diabetic foot ulcers.

This study found that human placenta extract may enhance hair growth by increasing PG-E2 and PG-F2a production while decreasing PG-D2 levels in cultured hair follicle keratinocytes.

In this review, platelet concentrates were found to show comparable efficacy to steroids and immunosuppressive drugs in treating oral lichen planus, with some studies reporting more benefits and others noting more severe adverse reactions with platelet treatments.

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.

This study found that programmed death-ligand 1 (PD-L1) levels correlated with the severity of alopecia areata, suggesting its potential as an indicator and possible target for new treatments.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

This review discusses the multifunctional role of PKM2 in promoting cardiac repair and regeneration, highlighting its potential as a therapeutic target in cardiovascular medicine, but reports no new experimental results.

This study found that TRPV3 activation in human sebocytes inhibits lipid synthesis and triggers proinflammatory cytokine expression, suggesting a role in the pathogenesis of dry skin-associated inflammatory dermatoses.

This review analyzes existing literature on platelet-rich plasma for hair loss, discussing its mechanisms and preparation, but reports no new clinical results and highlights the inconsistency of current evidence.

This study found that platelet-rich plasma improved healing and accelerated scar maturation in rat models of second-degree skin burns, especially noticeable after four weeks of treatment.

This review discusses peptide "biogenic stimulants" from human placenta extracts, highlighting their potential wide-ranging clinical applications across multiple diseases, and reports no new clinical results.

This review reports that platelet-rich plasma may be more effective for musculoskeletal conditions when prepared with high platelet doses and low leukocyte content, but further trials are needed to confirm optimal formulations.

This article reviews the potential of PRP as a treatment for spinal pain but calls for established use guidelines and protocols before wider clinical adoption, with no new clinical results reported.

In this study, serial platelet-rich plasma injections improved voice quality and mucosal wave ratings in patients with vocal fold scar, with patient-reported outcomes showing a consistent positive trend.