A Histological Study of the Possible Therapeutic Effect of Platelet-Rich Plasma on the Healing of Second-Degree Skin Burns and Prevention of Scar Formation in Adult Male Albino Rats

    Asmaa Mansour, Mona Sadek, Essam Laag, Ebtsam F. Okasha, Gehan Soliman
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    Studysummary This study found that platelet-rich plasma improved healing and accelerated scar maturation in rat models of second-degree skin burns, especially noticeable after four weeks of treatment.
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    This study investigated the therapeutic effects of platelet-rich plasma (PRP) on second-degree skin burns and scar formation in 70 adult male albino rats. The rats were divided into three groups, with Group III receiving a subcutaneous injection of PRP immediately after burn induction. The results showed that the PRP-treated subgroups (III-A and III-B) demonstrated enhanced healing and accelerated scar maturation compared to the untreated subgroups (II-A and II-B), with more significant effects observed after 4 weeks. The study concludes that PRP is effective in promoting healing and scar maturation in second-degree skin burns.
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