Phospholipase's Role in Maintaining and Restoring Skin and Hair Health

Phospholipases, enzymes that hydrolyze membrane phospholipids, play crucial roles in both the physiology and pathophysiology of the skin and hair. They are involved in lipid metabolism, which affects processes such as cell proliferation, angiogenesis, immune responses, and the maintenance of the skin's outer layer. Abnormal lipid synthesis from lysophospholipids is linked to diseases like alopecia, inflammation, and cancer. Understanding the molecular control of skin and hair by phospholipases could lead to new treatments for conditions such as hair loss, psoriasis, skin cancer, and other inflammatory skin disorders.