Silicone Elastomer Gel Impregnated with 20(S)-Protopanaxadiol-Loaded Nanostructured Lipid Carriers for Ordered Diabetic Ulcer Recovery

September 2019 in “ Acta Pharmacologica Sinica ”

Di Fei Sun, Shiyan Guo, Li Yang, Yaru Wang, Xiaohui Wei, Sha Song, Yiwei Yang, Yong Gan, Zhengtao Wang

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Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

research Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

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This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.

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This study found that dextran-based hydrogels promoted significant neovascularization and skin regeneration in mouse models of third-degree burns, without the need for additional growth factors or cells.