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This case report discusses a 15-year-old boy with pachyonychia congenita, identifying a keratin 17 gene mutation, and highlights the need for a national registry and more accessible genetic testing in India.

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.

This study found that central centrifugal cicatricial alopecia primarily affects adult women of African descent and suggests an association with traumatic hair care practices and delayed diagnosis.

This Health Policy report outlines the creation of evidence-based clinical practice guidelines and referral pathways for managing dermatological conditions in Pakistan's primary care setting, aiming to standardize care and improve patient outcomes.

This study found that the SUCCESS education programme did not increase the step count at three months for women with PCOS, highlighting the need for further evaluation over a longer duration.

This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.

In this study, a dog with canine pattern alopecia showed improved multifocal alopecia and general hair regrowth after 3 months of melatonin treatment.

This abstract describes the intended benefits of Kerablak Calcium Pantothenate Tablet for hair health but reports no new clinical study findings.

This study found cutaneous keratinic amyloid deposition in dogs and identified cytokeratin 5 as an amyloid precursor protein, revealing new insights into the etiology of cutaneous amyloidosis.

This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.

This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.

This review discusses the evolution and ongoing debate about the causes of central centrifugal cicatricial alopecia in African American women, without presenting new clinical findings.

This review discusses the potential use of prostate specific antigen as a diagnostic marker for hyperandrogenism in polycystic ovary syndrome but reports no new clinical results and calls for further research.

This review examines the patent literature on AKR1C3 inhibitors and suggests that although numerous potent inhibitors exist, further preclinical optimization is necessary before assessing their therapeutic potential in human diseases.

This study describes the development of a prototype clinical expert system that uses a belief rule-based inference methodology to improve the risk stratification and diagnosis of polycystic ovary syndrome by addressing uncertainties in clinical data and domain knowledge.

Early diagnosis and multidisciplinary care are crucial for managing PCOS in adolescents.

This study investigated a Labrador Retriever with paw pad hyperkeratosis and identified a unique de novo heterozygous missense variant in the GJB6 gene, suggesting its potential role in the condition, analogous to Clouston syndrome in humans, although differences between species may provide further insights.

This study found that hepatic KRT79 expression is regulated by PPARA and is significantly associated with liver stress, suggesting it may serve as a diagnostic marker for liver diseases.

This case report describes a Labrador retriever with arthrosis whose symptoms improved after sequential treatments including corticosteroids and tetracycline, leading to the resolution of dermatitis and nodular tumors.

In this study, topical inhibition of casein kinase 1 in mice was found to enhance melanocyte precursor migration and eumelanin production, suggesting potential applications for treating vitiligo and graying hair through KitL/c-Kit signaling pathway activation.

This study found no association between W locus allele variations and phenotypic traits like eye color, head spotting, and fur length in Turkish Van cats, suggesting other genetic factors should be explored.

This study introduced the KRDQN predictive framework, which outperformed existing methods in predicting adverse drug reactions and provided interpretable insights into drug mechanisms, aiding pharmacovigilance and clinical decision-making.

This study suggests that keratin expression in keratoacanthomas resembles that in the upper part of hair follicles, implying a potential origin, but it is indistinguishable from squamous cell carcinomas in terms of keratin reactivity.

This study found that activating PKM2 and Wnt/β-catenin signaling enhanced hair regrowth and hair follicle stem cell proliferation in mice, suggesting a potential alopecia treatment strategy.

This article reviews central centrifugal cicatricial alopecia, focusing on its multifactorial etiology and challenges in clinical diagnosis, and calls for more research and better treatment options.

This study emphasizes the genetic component of central centrifugal cicatricial alopecia, highlighting an atypical case involving an adolescent male within an African-American family.

The study found that CK15 expression, representing hair follicle stem cell activity, was reduced or absent in scarred primary cicatricial alopecia lesions, suggesting stem cell damage may contribute to the scarring process.

Treating primary cicatricial alopecia is difficult and requires evidence-based methods.