A Case Report of Central Centrifugal Cicatricial Alopecia in Two Generations

September 2017 in “ The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings ”

Ariana Eginli, Amy J. McMichael

central centrifugal cicatricial alopecia CCCA alopecia scarring alopecia inflammatory alopecia genetic component hair loss

TLDR CCCA can affect both genders and all ages, and it has a genetic component.

This case report described central centrifugal cicatricial alopecia (CCCA), an inflammatory and scarring form of alopecia, in an African-American family spanning two generations, including three members. Notably, it included an adolescent male, which is rare. The male patient had a history of scalp surgeries but no aggravating hair-grooming practices. The findings highlighted the genetic component of CCCA, suggesting that it should be considered in all new hair loss patients with a family history of CCCA, regardless of gender, hair care practices, or age at presentation.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community lost my hair in a single year of treatment at 20 years old

in Finasteride/Dutasteride 90 upvotes 1 year ago

A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

in Treatment 4 upvotes 6 years ago

Derma rolling, pumpkin seed oil, and daily massages helped regrow weak hairs on the crown. Nizoral shampoo and yoga also contributed to reducing scalp pain and stress.

community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

in Progress Pictures 88 upvotes 2 years ago

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.