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Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Certain genes control the color of human hair by affecting pigment production.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.