May 2026 in “Discover Chemistry.” This review presents recent advancements in bio-degradable polymers made through green chemistry, highlighting eco-friendly raw materials and methods, while also identifying challenges and future research areas to enhance their sustainability and commercial viability.
January 2024 in “CRC Press eBooks” This study discusses the potential of microbial exopolysaccharides as safer cosmetic ingredients compared to synthetic chemicals like parabens and BHA, which may cause skin damage and cancer; exopolysaccharides offer benefits like antimicrobial and antioxidative effects without harmful impacts.
22 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
5 citations
,
January 2024 in “Fermentation” This study found that fermenting porcine and equine placentas with a specific lactic acid bacterial strain enhanced the moisturizing abilities and cell proliferation properties compared to traditional placental extracts, suggesting their potential for cosmetic applications.
1 citations
,
January 2014 in “Asian Journal of Chemistry” This study identified the structures of cyclohexyl and phenyl analog impurities in finasteride using HPLC and spectral analysis.
15 citations
,
January 2020 in “RSC advances” In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.
72 citations
,
December 2009 in “Organic and Biomolecular Chemistry” This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.
August 2026 in “Journal of Cosmetic Dermatology” This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.
111 citations
,
August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
2 citations
,
November 2022 in “Biosensors” This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.
39 citations
,
January 1979 in “Journal of the Society of Cosmetic Scientists of Korea” This study observed that surfactants in cosmetic treatments can bind to keratinous tissues like hair and nails, affecting their tensile properties and possibly leading to deterioration depending on the specific detergents used.
18 citations
,
January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
April 2025 in “International Journal of Cosmetic Science” This study found that using 1,4-butylenediamine bismaleimide for hair perming through thiol-Michael click chemistry offers comparable efficiency to conventional oxidative methods, with enhanced durability and reduced damage to hair fibres, preserving mechanical, color, and surface properties.
June 2024 in “Ecotoxicology and Environmental Safety” This study observed that chronic and acute exposure to finasteride negatively impacted development, reproduction, and gene expression in Daphnia magna, highlighting the environmental risks of this pharmaceutical for freshwater ecosystems.
15 citations
,
April 2008 in “Steroids” This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.
8 citations
,
January 2008 in “Pediatric dermatology” Hair gels may cause split ends in children.
8 citations
,
September 2004 in “Contact dermatitis” Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
This review discusses the potential risks of formaldehyde in hair keratin treatments like Brazilian blow-dry, and reports no new clinical results; it emphasizes the need for greater safety assessments including occupational exposure.
1 citations
,
December 2023 in “Environmental pollution” This study quantified around 60 organic pollutants in hair samples from mothers and infants in Spain, finding significant correlations between pollutant levels and factors like residence, dietary habits, and maternal age, with common exposure sources identified for several pollutant classes.
5 citations
,
January 2000 in “Inhalation Toxicology” This study found that exposure to aqueous dispersion resin in aerosol form increased lung weights and caused histopathological changes in animals at higher concentrations, with a no-observable-effect level at 30 mg/m³.
September 2024 in “Journal of the American Academy of Dermatology” This study found that phenoxyethanol is the most common contact allergen in over-the-counter hair loss products, but its role in the development or exacerbation of frontal fibrosing alopecia remains unclear.
26 citations
,
February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
36 citations
,
July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
9 citations
,
July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
January 2007 in “Journal of Instrumental Analysis” This study found that using headspace capillary gas chromatography effectively determined the levels of residual organic solvents, including chloroform and dichloromethane, in finasteride with good separation and detection limits.
11 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that among the tested analogs, compound 4e was the most effective in inhibiting wax esters in vivo in the Golden Syrian hamster ear model.
4 citations
,
January 1994 in “Yakugaku zasshi” In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.
1 citations
,
January 1997 in “Skin research” Hinokitiol and pantothenylethylether in hair products can cause strong allergic reactions.
April 2023 in “Highlights in Science, Engineering and Technology” This review discusses the potential of flame retardant polyamide materials with glass fiber and graphene as a better performing alternative to acrylonitrile butadiene styrene for hair dryer housings, noting improvements in heat resistance, flame retardancy, durability, and UV resistance.
9 citations
,
July 2022 in “Journal of Cosmetic Dermatology” In this study, an ammonia-free and PPD-free permanent hair dye was tested on 50 ethnically diverse females, showing no cases of contact dermatitis and significant improvements in hair shine, color, moisturization, porosity, and combability after two dyeing sessions.