Polynucleotides HPT-Based Dermal Filler for Skin Rejuvenation: A Prospective Clinical Investigation

    August 2026 in “ Journal of Cosmetic Dermatology ”
    Chiara Teramo, Andrea Mattioli, Carolina Prussia
    Studysummary This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.
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    Research cited in this study 4

    1. Polynucleotides Versus Platelet-Rich Plasma for Androgenetic Alopecia: A Case Series JOJ Dermatology & Cosmetics · 2025
    2. The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review Journal of Cosmetic Dermatology · 2024
    3. Polynucleotides High Purification Technology for Asian Skin Regeneration and Rejuvenation Clinical Cosmetic and Investigational Dermatology · 2024
    4. Consensus Report on the Use of PN-HPT (Polynucleotides Highly Purified Technology) in Aesthetic Medicine Journal of cosmetic dermatology · 2020