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This study concluded that a synthesis process for finasteride from pregnenolone acetic ester is inexpensive, simple, and achieves a good yield of 36.5%.

This study reports the preparation of a key intermediate for finasteride and epristeride with a 69% overall yield from pregnenolone acetate.

In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This study found that nanoplastics' aggregation behavior on human skin, influenced by factors like concentration, photoaging, and organic constituents, affects their penetration potential through sweat glands and hair follicles, highlighting potential dermal exposure risks.

In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.

This study found that diphlorethohydroxycarmalol significantly increased prostaglandin $E_2$ synthesis in HaCaT human keratinocytes by upregulating COX-1 and COX-2 expression, suggesting potential benefits from elevated $PGE_2$ production.

This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.

This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.

This review discusses the adverse effects of hair care products, highlighting irritation dermatitis and allergic contact eczema due to common allergens like paraphenylenediamine and glycerol monothioglycolate, but reports no clinical results.

This study found that exposure to certain pesticides may be associated with delayed sexual maturation in adolescent males.

This study identified N-acyl arylsulfonamides, particularly N-(Boc-piperidine-4-carbonyl)-benzenesulfonamides, as steroid sulfatase inhibitors with improved cellular potency compared to previous compounds.

In this study, the researchers developed a cellulose-based hydrogel that provides sustained drug release with improved bioavailability and stability over time.

This study found that gelatin-resorcinol-formaldehyde caused peritoneal lesions and hair loss in rats and mice, indicating it is unsuitable for tubal occlusion and emphasizing the need for testing in multiple species before using compounds in humans.

This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.

PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.

In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.

This study found that TCDD significantly reduced EGF receptor binding in various animal models, linked to toxic symptoms like weight loss and developmental delays, with receptor phosphorylation persisting several days.

This study found that high exposure to plastics was associated with increased chances of irregular menstrual cycles and symptoms similar to polycystic ovary syndrome in adolescent girls.

This study found that among the tested analogs, compound 4e was the most effective in inhibiting wax esters in vivo in the Golden Syrian hamster ear model.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.

This study found that a human relevant potency threshold for estrogen receptor alpha agonism may serve as a health-protective screening tool, and highlights inference performance as essential for scientific confidence frameworks.

This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.

This article reviews the epidemiology, causes, clinical impact, and potential preventive strategies for Polycystic Ovarian Disease but reports no new research findings.

This case report details a 34-year-old woman's experience with infertility linked to PCOS, where surgical intervention and medication led to eventual pregnancy with complications.

This study found that bio-based waterborne polyurethanes derived from castor oil may offer effective hair-styling performance without skin irritation and appear to be safer for the environment compared to traditional hair sprays.

This review discusses the use of human and animal-derived placental and umbilical extracts in cosmetics, highlighting insufficient data to establish their safety and recommending they should not have metabolic or endocrine activity.