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This study found that securinine and ajmaline significantly inhibited hepatocellular carcinoma cell viability and induced apoptosis, with securinine showing lower toxicity to normal liver cells.

This study demonstrates that inhibiting SFRP1 with the antagonist WAY-316606 enhances hair growth in human scalp hair follicles ex vivo by facilitating Wnt signalling.

This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.

This study found that β-catenin signaling increases in newly born glial cells in the cortex after traumatic brain injury in mice, suggesting potential targets for enhancing recovery through the Wnt/β-catenin pathway.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.

This study demonstrated that intact adult human dermal papillae can induce hair growth when implanted into mouse hair follicles, highlighting their potential for advancing hair follicle biology and therapeutic approaches.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

This study found that overexpression of Hoxc13 in GC13 mouse models affects hair follicle differentiation by interacting with medulla-specific genes, particularly Foxq1, suggesting a regulatory pathway for medulla differentiation.

In this study using a mouse model, the researchers found that platelet-rich plasma significantly increased the number of newly formed hair follicles and decreased the time for hair formation compared to no treatment.

The researchers reported that the petroleum ether extract of Cuscuta reflexa may promote hair growth in testosterone-induced alopecia in mice by inhibiting the enzyme 5α-reductase.

Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.

This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.

This study identified a new genetic locus, ahl4, on distal Chromosome 10 that contributes to the early-onset, severe hearing loss in A/J mice compared to B6 mice.

This review examines the design strategies for creating conductive hydrogels with adjustable properties for various biomedical applications, highlighting their potential for supporting cell growth, wound healing, drug delivery, tissue regeneration, and biosensing.

This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.

This review discusses various surgical techniques for vitiligo repigmentation, noting that suction blister and split-thickness skin grafting have the highest success rates according to previous analysis, but reports no new results.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

In this study, a silk-inspired hydrogel system was developed that combines photodynamic therapy and wound healing, which may significantly reduce melanoma recurrence and enhance healing of infected wounds.

This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.

This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.

This study found that prevascularizing dermal matrices with adipose tissue-derived microvascular fragments improved vascularization and allowed earlier successful skin grafting in a bradythrophic wound model.

This study found that cyclosporin A treatment enhances hair growth in mice by inhibiting calcineurin-NFAT1 activity, which alters keratinocyte differentiation and apoptosis-related gene expression in hair follicles.

This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.

This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.

This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.

This study observed that hepatocyte adhesion to human hair keratin biomaterials was mediated by the hepatic ASGPR, as blocking this receptor reduced cell attachment.

This study found that prolactin plays a direct role in regulating the timing of hair growth cycles in mice by affecting the skin, rather than through other endocrine factors.

This study identified LY191704 as a specific noncompetitive inhibitor of human 5 alpha-reductase type 1, which may be useful in treating endocrine disorders related to DHT overproduction.

This study suggests that activating retinoic acid signalling can inhibit Wnt signalling and induce regression in certain skin tumors, providing potential therapeutic strategies for tumor regression.