8 citations
,
January 2007 in “Hair transplant forum international” This abstract reviews recent findings on the biology of isolated micrografts in hair restoration, emphasizing factors that enhance micrograft viability, but it does not report new experimental results.
37 citations
,
May 2007 in “International Journal of Pharmaceutics” The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.
January 2004 in “Dermatologic Surgery” This study found that storing hair micrografts in DMEM with apoptotic cell death inhibitors improved in vitro hair shaft elongation and reduced apoptosis, potentially enhancing micrograft transplantation outcomes.
10 citations
,
May 2006 in “Agricultural Sciences in China” This study found that a hydroponic buffer solution induced the formation of abundant long root hairs, termed "hedgehog roots," in several plant species but not in onions.
5 citations
,
October 2020 in “Agronomy” This study provides evidence that root hairs significantly enhance phosphorus uptake in barley when phosphorus availability is limited in the root zone.
40 citations
,
January 2018 in “Pharmaceutics” This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.
March 2025 in “International Journal of Trichology” In this study, researchers found that storing hair grafts at 37°C with 10% DMEM led to better graft survival compared to other solutions and temperatures, suggesting this method may enhance graft longevity and therapeutic outcomes.
10 citations
,
January 2004 in “Dermatologic Surgery” This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
May 2025 in “Plastic & Reconstructive Surgery Global Open” In this proof-of-concept study, researchers found that hair grafts preserved in preconditioned autologous platelet-rich plasma with photothermal biostimulation and phosphate-buffered saline remained viable for eight hours before transplantation, outperforming saline solution and Ringer's lactate by two hours.
January 2014 in “Journal of Central South University(Science and Technology)” This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.
Quickly fix tissue in formalin after excision to preserve it.
7 citations
,
January 1973 in “Calcified Tissue International” This study found that hair follicle tissue effectively induced mineral formation in calcium phosphate solutions, likely due to its nucleating ability, which was lost when the tissue was lyophilized and stored.
6 citations
,
July 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that a composition containing mannose-6-phosphate significantly reduced the total skin pore area by 24% in women after 56 days and by 30.2% in men after 7 days, suggesting its effectiveness in improving pore appearance by targeting dermal and epidermal modifications.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
11 citations
,
January 2006 in “Drug development and industrial pharmacy” In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.
41 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.
4 citations
,
June 2016 in “Journal of Pharmacopuncture” This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression.
3 citations
,
April 2016 in “Wound Repair and Regeneration” In this study, researchers developed a new murine model for transplanting vibrissae that mimics human hair transplantation, achieving successful hair growth in immune-deficient nude mice.
10 citations
,
May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
2 citations
,
January 2009 in “Journal of Drug Delivery Science and Technology” This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.
February 2024 in “Trends in Sciences” This study examined the stability of two 5α-reductase inhibitors in Tectona grandis extracts, finding that they are more stable in acidic environments and degrade rapidly under heat and light unless protected, suggesting the need for careful storage when developing anti-hair loss medications.
36 citations
,
November 1961 in “Archives of Dermatology” This abstract discusses the uncertain role of the vascular system in hair loss and highlights the unexplained aspects of various types of alopecias; it reports no new research findings.
9 citations
,
December 2013 in “Toxicological Research” This study found that Chamaecyparis obtusa oil increased hair follicle cell proliferation and maintained the anagen phase in mice, suggesting a potential for promoting hair growth.
61 citations
,
June 2014 in “Scientific Reports” This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.
43 citations
,
March 2009 in “Journal of Cellular and Molecular Medicine” This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.
26 citations
,
April 2011 in “Skin Research and Technology” This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.
22 citations
,
December 2014 in “Naunyn-Schmiedeberg's Archives of Pharmacology” This study found that baicalin activates Wnt/ß-catenin signaling in human dermal papilla cells, increasing alkaline phosphatase expression, growth factor expression, and promoting hair growth in mice.
4 citations
,
May 2019 in “Zeitschrift für Naturforschung C” This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
1 citations
,
November 2022 in “Pharmaceutical research” In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.