Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.

In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.

In this study, researchers found that barrier-enhancing formulations significantly reduced the penetration of proteins into hair follicles in porcine skin models, with effectiveness varying by formulation.

This commentary reviews the post-Finasteride syndrome and argues that while the condition's validity is debated, comprehensive guidelines are needed to address related risks and treatment options; it reports no new clinical results.

This study found that diphlorethohydroxycarmalol significantly increased prostaglandin $E_2$ synthesis in HaCaT human keratinocytes by upregulating COX-1 and COX-2 expression, suggesting potential benefits from elevated $PGE_2$ production.

In this study, an LC/MS/MS method was successfully developed to determine finasteride concentrations and study its pharmacokinetics in healthy male Chinese volunteers.

This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.

This study found that the diphosphonate ethan-1-hydroxy-1,1-diphosphonat was the most effective compound in preventing calcifications in rats induced by DHT, compared to other phosphatase inhibitors and polyphosphates tested.

This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.

This study reported that female pattern hair loss was prevalent in 11.8% of women aged 30 and older and was associated with high fasting glucose, fewer childbirths, oral contraceptive use, and excessive ultraviolet exposure.

This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.

This protocol outlines a study aiming to determine if combining 660 nm red laser photobiomodulation and microneedling increases hair density in female pattern hair loss, but it reports no results yet.

In this study, researchers found that a propylene glycol-free and alcohol-reduced topical foam containing minoxidil and finasteride remained chemically, physically, and microbially stable for 180 days when stored properly at room temperature in light-resistant containers.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

This study developed innovative silica/natural polysaccharide hybrid nanoparticles encapsulating plant-derived 5-alpha-reductase inhibitors, reporting effective controlled release at hair follicle pH and lower cytotoxicity, suggesting a promising delivery system for antiandrogenic treatments.

This study found that three sessions of injectable platelet-rich fibrin (i-PRF+) significantly improved hair follicle density, hair volume, and thickness, as well as patient satisfaction in women with female pattern hair loss, with only minor self-limited adverse effects reported.

This study explored a computer simulation method for selecting emulsion compositions in dermatology, finding that the PS biocomplex can be effectively used as an emulsifier or co-emulsifier, which streamlines the development process and reduces experimental demands.

In this study, the researchers developed a cellulose-based hydrogel that provides sustained drug release with improved bioavailability and stability over time.

Finasteride caused blisters on hands and feet.

This study found that female pattern hair loss was highly prevalent among a multiracial Brazilian population, affecting over 30% of women, and age was a significant risk factor.

This study evaluated a polyherbal hair oil made from natural ingredients and found that the F2 formulation demonstrated favorable physicochemical properties, good stability, and beneficial activities such as anti-dandruff, anti-hair fall, and hair growth promotion, identifying it as optimal for herbal hair care applications.

This report details a case study where a 40-year-old woman experienced allergic contact dermatitis and angioedema-like symptoms after using PPD-containing hair dye. Patch testing confirmed a positive reaction to PPD, highlighting the substance's potential to cause both T-cell and IgE-mediated hypersensitivity reactions.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This study highlights the crucial role pharmacists play in the aesthetic field, emphasizing their technical knowledge in ensuring safe and informed use of cosmetic products, which enhances professional recognition and promotes more secure and ethical aesthetic practices.

This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.

This study used Density Functional Theory to calculate finasteride's molecular properties, finding the GGA/PW91 method aligns well with experimental data and identifying key reactive sites for chemical interactions.

This article discusses the potential role of nutritional ingredients, such as thiols and tannins, in triggering pemphigus, and reports no new empirical findings.