pH Stimulus-Responsive Hybrid Nanoparticles: A System Designed for Follicular Delivery of Brazilian Plant-Derived 5-Alpha-Reductase Enzyme Inhibitors

    December 2023 in “ International Journal of Pharmaceutics ”
    Renata Pinho Morais, Carolina Camargo de Oliveira, Izabel C. Riegel‐Vidotti, Cláudia Eliana Bruno Marino
    Studysummary This study developed innovative silica/natural polysaccharide hybrid nanoparticles encapsulating plant-derived 5-alpha-reductase inhibitors, reporting effective controlled release at hair follicle pH and lower cytotoxicity, suggesting a promising delivery system for antiandrogenic treatments.
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    Research cited in this study 14

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    13. Double-Blind, Randomized, Placebo-Controlled Trial of a Cream Containing the Stryphnodendron Adstringens (Martius) Coville Bark Extract for Suppressing Terminal Hair Growth Journal of the European Academy of Dermatology and Venereology · 2009
    14. Diagnóstico etiológico do hirsutismo e implicações para o tratamento Revista Brasileira Ginecologia e Obstetrícia · 2009