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In this study, researchers found that fenugreek seed extract reduced prostate size, DHT levels, and cell proliferation in a testosterone-induced BPH rat model while modulating various genetic expressions, suggesting its potential as an alternative treatment for benign prostatic hyperplasia.

This study developed two sensitive spectrophotometric methods to accurately determine finasteride in pure and tablet forms, demonstrating linear response and compliance with ICH guidelines.

In this study using a mouse model, researchers observed that topical nifedipine cream at 0.3% concentration promoted hair growth more effectively than 2% minoxidil solution, suggesting that nifedipine may have potential as a hair growth treatment.

This study found that evaluating nasal breathing parameters in children with adenoiditis may help assess the effectiveness of conservative treatments during outpatient care.

This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

This study identified the structures of cyclohexyl and phenyl analog impurities in finasteride using HPLC and spectral analysis.

This study found that the presence of benzeneseleninic acid in commercial anhydride samples lowered the reaction rate during the oxidation of a finasteride intermediate compared to pure anhydride.

This study suggests that using antihistamines alongside a regimen of topical corticosteroid and superficial cryotherapy may enhance hair regrowth in patients with mild to moderate alopecia areata.

Adding diltiazem to a beta blocker can cause dangerously slow heart rates.

This review discusses the current understanding of propranolol's use in treating infantile hemangiomas, covering its indications, effectiveness, side effects, and ongoing clinical trials, without presenting new clinical results.

In this study, 5 mg of finasteride per day significantly improved urinary symptoms and reduced prostate volume in men with benign prostatic hyperplasia, but increased the risk of sexual dysfunction.

This study demonstrated that 12 months of 5 mg daily finasteride treatment reduced prostate volume, dihydrotestosterone, and prostate-specific antigen levels, while improving urinary flow rates and symptom scores in benign prostatic hyperplasia patients.

This study found that combining cyproterone acetate with topical eflornithine was a safe and effective treatment for facial hirsutism in women.

This letter to the editor raises concerns about minoxidil, an arterial vasodilator also used for androgenic alopecia, noting that overdose can cause severe side effects such as distributive shock, pulmonary edema, and myocardial ischemia.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This study used NMR spectroscopy and other techniques to fully assign the proton and 13C spectra of the 5α-reductase inhibitor finasteride.

This study found that Ecklonia cava polyphenols increased human dermal papilla cell proliferation and extended hair shaft length in vitro and ex vivo, suggesting potential as a therapeutic candidate for hair loss.

This review reports that combination therapy with 5α-reductase inhibitors and α1-receptor blockers does not appear to benefit patients with benign prostatic hyperplasia and prostate volumes up to 40–45 ml, but may be more effective for larger prostate volumes.

The researchers reported finding 53 therapeutic and skincare products for hirsutism and hypertrichosis in Polish pharmacies and drugstores, identifying dienogest and cyproterone acetate as common active ingredients for hirsutism. They noted promising new treatments include eflornithine, acyclovir, licorice, and vitamin D.

This review summarizes a meta-analysis suggesting that finasteride is most effective for improving symptoms and urinary flow in men with large prostates experiencing benign prostatic hyperplasia.

This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.

This study found that isoliensinine, a natural compound identified from a database, effectively prevented stress-induced hair greying in mice by blocking β-2 adrenergic receptors on melanocyte stem cells in hair follicles.

In this experimental study on Holtzman rats with induced benign prostatic hyperplasia, the researchers observed that the extract of Physalis peruviana (aguaymanto) had a greater therapeutic effect on prostate weight reduction and prostatic epithelium height compared to finasteride and terazosine.

This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.

This publication discusses the political rationale behind the French regulator ANSM's decision to withdraw Diane®-35 from the market, in response to health concerns associated with third-generation oral contraceptives.

In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.

This study found that nanoemulsion formulations with oleic acid or eucalyptol significantly enhanced the delivery and retention of caffeine through hair follicles and surrounding skin regions.