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Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

JAK inhibitors like tofacitinib can effectively treat severe alopecia areata.

Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Some common medications can harm male fertility, but many effects can be reversed.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Combining laser hair removal with topical eflornithine is recommended for better results in treating unwanted facial hair.

Menopause affects hair and skin; more research needed for treatment.

Immune cells affect hair growth and could lead to new hair loss treatments.

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

DA-9401 helps protect rat testis from finasteride damage.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.