This study developed and evaluated a polyherbal solid shampoo bar using natural ingredients like Amla, Soapnut, Hibiscus, and Aloe vera, and found it to be an effective, safe, and sustainable alternative to conventional hair care products, with good cleansing and lathering properties.
March 2022 in “INDIAN JOURNAL OF APPLIED RESEARCH” This study found that the formulated shampoo using alcoholic extracts of Hibiscus rosa-sinensis demonstrated antimicrobial and antifungal activity and met all standard evaluation criteria, offering a potentially safer alternative to synthetic shampoos without harmful preservatives like paraben.
January 2022 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This study suggests that coffee ground extract may accelerate hair growth in rabbits, potentially due to its caffeine content.
June 2021 in “Journal of Pharmaceutical Care Anwar Medika” This study investigated the physical stability of hair tonic formulations made from ethanol extract of cayenne pepper leaves, finding that formulations with specific concentrations of propylene glycol and ethanol had good physical stability.
June 2021 in “International Journal of Pharma and Bio Sciences” This study found that a wheat-protein based herbal shampoo with natural ingredients demonstrated good conditioning performance, cleansing properties, and surface tension, helping to clear dirt, dandruff, and promote hair strength and darkness without causing hair damage, but further work is needed to enhance its quality.
June 2022 in “International Journal of Advanced Research in Science, Communication and Technology” This study aimed to develop a herbal hair serum to enhance hair growth and prevent hair loss, addressing common issues like extreme hair loss in younger populations caused by lifestyle factors such as stress and dietary habits.
193 citations
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August 1985 in “Endocrinology” This study found significant species differences in the enzyme activity and inhibitor affinities of prostatic 5α-reductases from rats, dogs, and humans, with variable potencies for different 3-oxo-4-azasteroid inhibitors across species.
70 citations
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June 1993 in “Biochemistry” This study found that the binding of finasteride to the enzyme 5a-reductase occurs at a slower rate than previously assumed, complicating the estimation of its real inhibitory constant.
6 citations
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July 2024 in “Heliyon” This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.
6 citations
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January 2022 in “Database” This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
April 2022 in “Jurnal Penelitian Farmasi dan Herbal” In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.
January 2020 in “Journal of Pharmacognosy and Phytochemistry” This study observed that a polyherbal hair oil made from virgin coconut oil and extracts of nine different herbs demonstrated effectiveness in promoting hair growth with a cooling effect and no reported side effects, based on various evaluated properties.
July 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This study developed and tested a Brahmi-based herbal shampoo, finding it effective for cleaning hair, maintaining suitable pH and foaming properties, and being stable and safe for regular use without irritation or damage.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and tested a natural polyherbal shampoo powder, finding it to have strong anti-dandruff and antifungal properties, good foaming capacity, acceptable pH, and no skin irritation, suggesting it as a safe and eco-friendly alternative to synthetic shampoos.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a low-viscosity triamcinolone acetonide serum, used with a derma stamp microneedling device, to improve targeted treatment of alopecia areata, reporting favorable drug solubility, spreadability, and permeation to hair follicles, while maintaining skin safety.
January 2026 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study reports that disruptions to the scalp microbiome from invasive cosmetic procedures may contribute to dermatological conditions, and suggests incorporating microbiome assessments and personalized restoration programs into trichological and dermatological practices.
This review discusses potential advancements in topical dutasteride formulations for treating androgenic alopecia and reports no clinical results, highlighting a focus on improving skin penetration and availability.
115 citations
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November 2004 in “Brain Behavior and Immunity” This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.
1 citations
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August 2021 in “International journal of scientific research in science and technology” This study evaluated a polyherbal hair oil, containing natural ingredients like Hibiscus and Aloe Vera in a coconut oil base, for its phytochemical properties, antimicrobial activity, and potential to reduce dandruff and hair loss while promoting hair growth.
In this study, researchers developed and tested an herbal hair serum containing natural ingredients like banana flower extract and orange oil, which was stable and pH-balanced, with preliminary user feedback suggesting improved hair texture, reduced hair fall, and increased hair density.
2 citations
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January 2025 in “International Journal of Pharmaceutical Research and Applications” This study formulated an herbal shampoo using natural extracts and compared its physicochemical properties, such as pH and foam consistency, with commercial shampoos, finding that both performed similarly in conditioning tests conducted with twenty volunteers.
May 2023 in “Jurnal Penelitian Farmasi & Herbal” In this study, researchers developed cucumber-based hair tonics and tested their physical stability, finding them to be homogenous and meet requirements for color and pH, suggesting potential use as a remedy for hair loss.
December 2025 in “International Journal of Pharmaceutical Sciences Review and Research” In this study, a newly developed polyherbal hair oil exhibited promising characteristics, including a beneficial pH and antimicrobial activity against Staphylococcus aureus, with preliminary tests suggesting it supports scalp and hair health without adverse effects.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effectiveness of three formulated hair conditioners—Herbal, Synthetic, and Ayurvedic—using organoleptic and physicochemical tests like pH, Dirt Dispersion, and Stability, with the main aim to develop a product that meets user compliance and desired hair care effects.
December 2022 in “INDIAN DRUGS” This study evaluated different herbal hair oil formulations and found that formulation F3 had the most favorable physical properties, such as pH and viscosity, among those tested.
1 citations
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April 2019 in “Acta Medica Philippina” This review discusses emerging evidence on azathioprine's efficacy and safety for severe alopecia areata, reporting sustained response in many patients but emphasizing the need for controlled trials.
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study developed and tested a herbal hair growth tonic using medicinal plant extracts on animal models, reporting higher anagen/telogen ratio, follicular density, and hair length compared to controls, suggesting it as a potential natural alternative to synthetic products.
September 2023 in “International journal of drug delivery technology” This study developed and tested an herbal shampoo containing tea, ashwagandha, sandalwood, and nagarmotha, finding it exhibited good cleansing properties and effectively controlled Candida and Malassezia fungi.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and tested a herbal shampoo incorporating natural extracts like curry leaves, neem, and fenugreek, finding that these formulations reduced dandruff and improved hair health while being non-irritating and stable; the curry leaf shampoo excelled in cleansing performance.