June 2023 in “Journal of Pharmaceutical and Health Research” In this study with guinea pigs, a hair tonic containing 0.001% caffeine significantly stimulated hair growth, showing higher effectiveness with an average hair length of 18.294 mm compared to a tonic with 0.005% caffeine concentration, which resulted in an average hair length of 16.610 mm.
June 2022 in “Jurnal Health Sains” This review discusses plant-based alternatives for hair tonic formulations to address hair loss and contains no new clinical results, advocating for plant extracts as safer options than synthetic ingredients.
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January 2012 in “International Journal of Trichology” Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
September 2023 in “Journal of The American Academy of Dermatology” In this study, the authors conducted a systematic review to examine the effectiveness of caffeine supplementation on hair growth, finding the current evidence for caffeine's efficacy remains unclear.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.