December 2025 in “PubMed” In this study, researchers found that a propylene glycol-free and alcohol-reduced topical foam containing minoxidil and finasteride remained chemically, physically, and microbially stable for 180 days when stored properly at room temperature in light-resistant containers.
January 2024 in “World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany” Polisorbate 20 is not suitable for curl creams due to instability.
September 2023 in “Journal of the American Academy of Dermatology” The hair care routine effectively improved scalp health and reduced fungus in children with kinky hair.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
May 2023 in “Pharma xplore : jurnal sains dan ilmu farmasi” In an animal study, researchers found that a hair tonic containing a 1:1 ratio of kelor and rambutan leaf extracts led to similar hair growth in rabbits compared to a minoxidil control, with average hair lengths of 3 cm versus 2.025 cm, respectively.
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
12 citations
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
April 2025 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, a hair tonic containing fragrant pandan leaf extract and virgin coconut oil was formulated and evaluated, with most variations demonstrating physical stability except for one formulation, which showed instability in the specific gravity test.
37 citations
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October 2017 in “Saudi pharmaceutical journal” This study reports that six shampoo brands in Saudi Arabia generally comply with the national specifications, demonstrating good physicochemical properties such as foam stability and pH levels.
35 citations
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September 1972 in “Journal of Biological Chemistry” This study observed that the binding of certain hormones in rat skin varies cyclically with the hair cycle phases, with testosterone showing maximum binding in the catagen phase.
13 citations
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May 2018 in “Urologic Oncology: Seminars and Original Investigations” In this study, researchers found no significant difference in bladder cancer incidence between men treated with finasteride and those given a placebo, suggesting that reduced dihydrotestosterone levels may not impact bladder cancer risk.
4 citations
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November 2017 in “Journal of Cosmetic Dermatology” This study found that polyquaternium-68 at pH 9 achieved the greatest hair deposition, while polyquaternium-44 demonstrated the best wash resistance at pH 6.
4 citations
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January 1994 in “Yakugaku zasshi” In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.
1 citations
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January 2022 in “Indonesian Journal of Pharmaceutical Science and Technology” This study evaluated a 20% cinchona extract cream and found it increased hair growth length and mass in guinea pigs, demonstrated good physical stability, and did not irritate rabbit skin.
1 citations
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January 2014 in “Jurnal Tata Rias” In this study, the hair tonic with a 3:3 avocado extract to honey ratio was most preferred by panelists and may be suitable for preventing hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In laboratory tests, this study evaluated several skin cream formulations and reported that formulation F6 showed superior stability and strong antioxidant potential, while all formulations were stable, of uniform consistency, had a suitable pH, and were non-irritant to the skin.
In this study, researchers developed a standardized Ayurvedic hair pack using natural ingredients like Shikakai and Amla and confirmed its safety and pH suitability; they concluded it could be a scientifically validated alternative to synthetic hair products.
August 2024 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This study reports that a carbopol gel formulation with melatonin shows potential for extended drug release and biocompatibility in dermal applications due to its favorable bio-pharmaceutical properties.
July 2022 in “International journal of Ayurvedic medicine” This study evaluated a newly formulated polyherbal anti-dandruff shampoo that incorporates natural ingredients, such as Neem and Aloe vera, to effectively clean hair, control dandruff, and promote hair growth without using harmful synthetic chemicals.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights a polyherbal hair formulation that combines various natural ingredients, reporting potential benefits in improving scalp circulation, strengthening hair, and promoting regrowth, which might offer a safer alternative for managing male pattern baldness compared to synthetic drugs.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a herbal anti-dandruff shampoo using natural ingredients, finding that it effectively reduced dandruff, improved scalp and hair health, and presented an economical and safe alternative to synthetic shampoos without significant skin irritation.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the development of a herbal anti-dandruff shampoo using natural ingredients like fenugreek, curry leaves, and neem, finding it effective in reducing dandruff and nourishing the scalp without causing irritation, and suggesting it as a safe and economical alternative to synthetic shampoos.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a herbal anti-dandruff shampoo utilizing natural extracts like fenugreek, curry leaves, and neem, finding it safe, effective, and stable for topical use, with the curry leaf variety showing superior cleansing performance.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review summarizes current research on natural hair dyes, reporting that plant-based formulations can safely provide viable colors on gray hair with minimal irritation compared to synthetic options but face challenges in color range and consistency.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal hair oil formulated with medicinal plants and base oils like coconut and almond, reporting it as safe and effective in promoting hair growth, improving scalp health, and offering an economical alternative to synthetic hair care products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that a newly formulated polyherbal hair oil, containing ingredients like amla and neem, may safely promote hair growth and overall scalp health as an alternative to synthetic products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers formulated and evaluated an herbal hair smoothing cream containing natural ingredients like aloe vera and coconut oil, reporting significant improvements in hair smoothness, softness, shine, and manageability without irritation, suggesting it as a safer alternative to traditional hair straightening products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated herbal hair smoothing cream using ingredients like aloe vera and coconut oil improved hair texture, such as smoothness and shine, without irritation, offering a safer alternative to conventional products.
January 2026 in “ChemistrySelect” This study demonstrates that a newly developed bio-based, dual-phasic hair serum offers a sustainable and effective alternative to traditional silicone-based serums, enhancing hair cuticle integrity and consumer appeal while supporting environmentally friendly formulation design.